Results 41 to 50 of about 687,018 (362)

Characterization of Vibrio parahaemolyticus clinical strains from Maryland (2012-2013) and comparisons to a locally and globally diverse V. parahaemolyticus strains by Whole-Genome Sequence Analysis

Frontiers in Microbiology, 2015
Vibrio parahaemolyticus is the leading cause of foodborne illnesses in the US associated with the consumption of raw shellfish. Previous population studies of V.
Julie eHaendiges, Ruth eTimme, Marc William Allard, Robert A Myers, Robert A Myers, Eric Wayne Brown, Narjol eGonzález-Escalona   +6 more
doaj   +1 more source

Exploring racial disparities in treatment patterns and outcomes for patients with multiple myeloma using real world data

Blood Cancer Journal, 2022
This retrospective observational study evaluated racial disparities among Black and White patients with multiple myeloma (MM). We included patients from a longitudinal de-identified EHR-derived database who had ≥2 visits recorded on or after 1/1/2011 ...
Kathleen Maignan, Lola A. Fashoyin-Aje, Aracelis Z. Torres, Laura L. Fernandes, Thomas Gwise, Shrujal B. Baxi, James P. Roose, Donna R. Rivera, Yuan Li Shen, Paul G. Kluetz, Nicole J. Gormley   +10 more
doaj   +1 more source

Development of Drug-Device Combination Products and Generic Substitution in the United States

INNOVATIONS in Pharmacy
Generic drug products approved and marketed in the United States include a variety of drug classes and dosage forms along with drug-device combination products (DDCPs).
YoonJung Lee, Ila Srivastava, Katharine B. Feibus, Elizabeth R. Bielski, Lolita Sterrett, Danielle Harris, Markham C. Luke   +6 more
doaj   +1 more source

Mechanical and leakage integrity testing considerations for evaluating the performance of tissue containment systems

Scientific Reports, 2023
Tissue containment systems (TCS) are medical devices that may be used during morcellation procedures during minimally invasive laparoscopic surgery.
Alexander Herman, Nandini Duraiswamy, Poulomi Nandy, Veronica Price, George Gibeily, Prasanna Hariharan   +5 more
doaj   +1 more source

Recovery and growth potential of Listeria monocytogenes in temperature abused milkshakes prepared from naturally contaminated ice cream linked to a listeriosis outbreak

Frontiers in Microbiology, 2016
The recovery and growth potential of Listeria monocytogenes was evaluated in three flavors of milkshakes (vanilla, strawberry, and chocolate) that were prepared from naturally contaminated ice cream linked to a listeriosis outbreak in the U.S.
Yi eChen, Emma eAllard, Anna eWooten, Minji eHur, Ishani eSheth, Anna eLassri, Thomas S Hammack, Dumitru eMacarisin   +7 more
doaj   +1 more source

Estimated Costs of Pivotal Trials for Novel Therapeutic Agents Approved by the US Food and Drug Administration, 2015-2016

JAMA Internal Medicine, 2018
Importance A critical question in health care is the extent of scientific evidence that should be required to establish that a new therapeutic agent has benefits that outweigh its risks.
Thomas J. Moore, Hanzhe Zhang, G. Anderson, G. Caleb Alexander   +3 more
semanticscholar   +1 more source

Peptide Nucleic Acid Probe Detection of Mutations in Mycobacterium tuberculosis Genes Associated with Drug Resistance

BioTechniques, 2002
The emergence of drug-resistant strains of Mycobacterium tuberculosis is a serious public health problem. Many of the specific gene mutations that cause drug resistance in M. tuberculosis are point mutations. We are developing a PCR-peptide nucleic acid (
L.E. Bockstahler, Z. Li, N.Y. Nguyen, K.A. Van Houten, M.J. Brennan, J.J. Langone, S.L. Morris   +6 more
doaj   +1 more source

Lociq provides a loci-seeking approach for enhanced plasmid subtyping and structural characterization

Communications Biology, 2023
Antimicrobial resistance (AMR) monitoring for public health is relying more on whole genome sequencing to characterize and compare resistant strains. This requires new approaches to describe and track AMR that take full advantage of the detailed data ...
Lucas Harrison, Shaohua Zhao, Cong Li, Patrick F. McDermott, Gregory H. Tyson, Errol Strain   +5 more
doaj   +1 more source

Unapproved Pharmaceutical Ingredients Included in Dietary Supplements Associated With US Food and Drug Administration Warnings

JAMA Network Open, 2018
Key Points Question What are the trends across adulterated dietary supplements associated with a warning released by the US Food and Drug Administration from 2007 through 2016?
Jenna N. Tucker, Tessa Fischer, Laurence Upjohn, D. Mazzera, Madhur Kumar   +4 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source