Results 131 to 140 of about 1,171,437 (339)

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

open access: yesAdvanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li   +10 more
wiley   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

open access: yesAdvanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang   +6 more
wiley   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

open access: yesAdvanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins   +2 more
wiley   +1 more source

Influence of Media on Overweight and Obesity Among Latino Youth [PDF]

open access: yes, 2011
Outlines findings about how media marketing affects the health-related behaviors of Latino youth, including trends in television viewing, fast-food advertisement in low-income Latino communities, and snacking and caloric intake.
Amelie Ramirez   +2 more
core  

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

open access: yesAdvanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran   +5 more
wiley   +1 more source

Femtosecond Single‐ and Double‐Pulse Fabrication of Periodic Nanostructures on Stainless Steel for Surface‐Enhanced Raman Spectroscopy

open access: yesAdvanced Engineering Materials, EarlyView.
Periodic submicron features are fabricated on 304 stainless steel using single and double femtosecond laser pulses. By adjusting polarization, fluence, and inter‐pulse delay, 1D and 2D nanostructures are formed. Enhanced hydrophobicity and dense surface‐enhanced Raman spectroscopy hotspots enable analyte detection down to 10−10 M with good ...
Balaji Baskar   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy