Results 71 to 80 of about 1,063,156 (290)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Effect of defoliation height on regrowth of timothy and meadow fescue in the generative and vegetative phases of growth [PDF]

open access: yes, 2003
Post-defoliation carbohydrate stores, leaf area and the number of active meristems are important factors affecting the subsequent regrowth of grasses. Defoliation height affects the magnitude of all these factors.
Virkajärvi, Perttu
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Nutritional significance of velvet bean (Mucuna pruriens) and opportunities for its processing into value-added products

open access: yesJournal of Agriculture and Food Research
Underutilized legume comprises vital nutrients with a higher proportion of protein (23-43 %) equal to soybean, and lima bean and greater than chickpea and green pea. In addition, it has a good calorific value, carbohydrates, vitamins, and minerals.
D. Sowdhanya   +6 more
doaj   +1 more source

PENGELOMPOKAN SAYURAN BERDASARKAN KEMIRIPAN KANDUNGAN GIZI

open access: yesE-Jurnal Matematika, 2018
One of the either of health maintain is trough the food consumption pattern that fulfill nutrient content. Vegetables are needed to body as source of vitamin, mineral and fiber in gaining healthy food pattern as a recommended guidance of nutrient ...
AYU SANDRA TIARA DEWI   +2 more
doaj   +1 more source

Changes in Indonesian Food Consumption Patterns and their Nutritional Implications [PDF]

open access: yes
This study examines changes in Indonesian food consumption during 1996-2002 which included the period of the Asian financial crisis in late 1997/98. This paper analyses the nutritional implications of the changes in terms of the level and composition of ...
Elkana Ngwenya, Ranjan Ray
core   +1 more source

Tools to balance increased food security with decreased emissions [PDF]

open access: yes, 2014
Almost every aspect of trying to reduce climate change involves weighing alternatives and then setting priorities. For example, you could plant trees to store carbon, but that might reduce the amount of food you can grow on the same land.
CGIAR Research Program on Climate Change, Agriculture and Food Security
core  

Marketers’ Use Of Alternative Front-Of-Package Nutrition Symbols: An Examination Of Effects On Product Evaluations [PDF]

open access: yes, 2017
How front-of-package (FOP) nutrition icon systems affect product evaluations for more and less healthful objective nutrition profiles is a critical question facing food marketers, consumers, and the public health community.
Andrews, J. Craig   +4 more
core   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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