Results 51 to 60 of about 1,832,654 (296)
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
The Russia-Ukraine Conflict: Its Implications for the Global Food Supply Chains
Food is one of the most traded goods, and the conflict in Ukraine, one of the European breadbaskets, has triggered a significant additional disruption in the global food supply chains after the COVID-19 impact.
Sandeep Jagtap+12 more
doaj +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Modelling Fresh Strawberry Supply "From-Farm-to-Fork" as a Complex Adaptive Network [PDF]
The purpose of this study is to model and thereby enable simulation of the complete business entity of fresh food supply. A case narrative of fresh strawberry supply provides basis for this modelling. Lamming et al.
Engelseth, P., Karlsen, A., Verwaart, T.
core +4 more sources
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale+9 more
wiley +1 more source
No. 03: Pathways to Insecurity: Food Supply and Access in Southern African Cities [PDF]
As in many parts of the world, supermarket expansion and control of food supply chains is having a major impact on the quality, quantity and price of food available to urban residents.
Crush, Jonathan, Frayne, Bruce
core +1 more source
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu+3 more
wiley +1 more source
The organic food supply chain in relation to information management and the interaction between actors [PDF]
Conventional retailers play a significant role in selling organic food, and therefore, it is important to understand how the demand - supply chain of organic food works as an element of the conventional food system.
Kottila, Marja-Riitta+2 more
core
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam+2 more
wiley +1 more source