Results 111 to 120 of about 2,377,544 (376)

Os Negativos da História: A Ferrovia-Fantasma e o Fotógrafo-Cronista

open access: yesResgate, 1993
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Francisco Foot Hardman
doaj  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

An alternative SU(4) x SU(2)L x SU(2)R model

open access: yes, 1997
A simple alternative to the usual Pati-Salam model is proposed. The model allows quarks and leptons to be unified with gauge group $SU(4) \otimes SU(2)_L \otimes SU(2)_R$ at a remarkably low scale of about 1 TeV.
Foot, R.
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Acute compartment syndrome after a lapidus-akin procedure: A case report

open access: yesFoot & Ankle Surgery: Techniques, Reports & Cases, 2022
Acute compartment syndrome is a limb threatening condition typically associated with traumatic injury; however, it can be associated with surgical procedures such as abdominal and pelvic surgeries as well as hip and knee arthroplasty. In this case report,
Rimvydas P. Statkus, DPM FACFAS   +3 more
doaj  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Dissipative dark matter and the rotation curves of dwarf galaxies

open access: yes, 2016
There is ample evidence from rotation curves that dark matter halos around disk galaxies have nontrivial dynamics. Of particular significance are: a) the cored dark matter profile of disk galaxies, b) correlations of the shape of rotation curves with ...
Foot, R.
core   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

A simple explanation of the PVLAS anomaly in spontaneously broken mirror models

open access: yes, 2007
The PVLAS anomaly can be explained if there exist millicharged particles of mass $\stackrel{
A. Kobakhidze   +18 more
core   +3 more sources

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