Results 61 to 70 of about 2,194,974 (347)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Electroweak Higgs as a pseudo-Goldstone boson of broken scale invariance
, 2007 We point out that it is possible to associate the electroweak Higgs boson with the pseudo-Goldstone boson of broken scale invariance, thus resolving the hierarchy problem in a technically natural way.
Archil Kobakhidze +17 more
core +2 more sources
Toward Machine-Learning-Based Decision Support in Diabetes Care: A Risk Stratification Study on Diabetic Foot Ulcer and Amputation [PDF]
, 2021 Zeinab Schäfer +5 more
openalex +1 more source
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974 An epidemiological investigation of bone and joint abnormalities in a Xhosa population revealed 6 females with a condition characterised by marked lateral deviation of the fifth toes. This disorder does not seem to have been previously described, and we therefore propose that it should be named 'Transkei foot'.
Schwartz, P.A. +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Moving the British National Collections
Liber Quarterly: The Journal of European Research Libraries, 2000 There is no point in rehearsing the lengthy saga of building the new British Library in North London. The media made much of it − much of it inaccurate − and the Library, its staff and its users are now only too pleased to put all that behind and are ...
Mirjam M. Foot
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Emergency Medicine International, 2022 Objective. The aim of this study is to study the application effects of doctor-nurse-patient co-decision-making nursing intervention based on evidence-based problems in the rehabilitation of acute ankle lateral collateral ligament injury. Methods.
Nian Wei, Yuehui Du, Shiyu Chen
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Journal of Orthopaedic Surgery and Research, 2021 Background There have been debates on the necessity of fibular osteotomy (FO) in supramalleolar osteotomy (SMOT) for the treatment of varus ankle osteoarthritis.
Jing-Qi Liang +8 more
doaj +1 more source