Results 71 to 80 of about 2,090,287 (327)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

An alternative SU(4) x SU(2)L x SU(2)R model

open access: yes, 1997
A simple alternative to the usual Pati-Salam model is proposed. The model allows quarks and leptons to be unified with gauge group $SU(4) \otimes SU(2)_L \otimes SU(2)_R$ at a remarkably low scale of about 1 TeV.
Foot, R.
core   +1 more source

The Diabetic Foot

open access: yesCurrent Pharmaceutical Design, 2018

Andor W. J. M. Glaudemans   +2 more
openaire   +4 more sources

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

The efficacy of autologous matrix-induced chondrogenesis (AMIC) for osteochondral lesions of the talus in the mid-long term: a systematic review and meta-analysis

open access: yesJournal of Orthopaedic Surgery and Research
Purpose The objective of this study was to provide a comprehensive review of the existing literature regarding the treatment of osteochondral lesions of the talus (OLT) using autologous matrix-induced chondrogenesis (AMIC), while also discussing the mid ...
Ning Jiang   +4 more
doaj   +1 more source

Republication of “Most Readmissions Following Ankle Fracture Surgery Are Unrelated to Surgical Site Issues: An Analysis of 5056 Cases”

open access: yesFoot & Ankle Orthopaedics, 2023
Background: Ankle fracture surgeries are generally safe and effective procedures; however, as quality-based reimbursement models are increasingly affected by postoperative readmission, we aimed to determine the causes and risk factors for readmission ...
Michael C. Fu MD, MHS   +5 more
doaj   +1 more source

\nu_\mu<->\nu_\tau vs \nu_\mu<->\nu_s solutions for the atmospheric neutrino problem

open access: yes, 1998
The $\nu_\mu \leftrightarrow\nu_\tau$ and $\nu_\mu \leftrightarrow\nu_s$ solutions to the atmospheric neutrino problem are compared with Superkamiokande data.
Akhmedov   +28 more
core   +1 more source

Association of Planus Foot Posture and Pronated Foot Function With Foot Pain: The Framingham Foot Study [PDF]

open access: yesArthritis Care & Research, 2013
ObjectiveTo examine the associations of foot posture and foot function to foot pain.MethodsData were collected on 3,378 members of the Framingham Study cohort who completed foot examinations in 2002–2008. Foot pain (generalized and at 6 locations) was based on the response to the following question: “On most days, do you have pain, aching or stiffness ...
Menz, Hylton B.   +4 more
openaire   +3 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

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