Results 91 to 100 of about 123,988 (310)

Fibrodysplasia ossificans progressiva in children (review and clinical analysis of 5 case reports)

Travmatologiâ i Ortopediâ Rossii, 2016
Ossificans progressive fibrodysplasia (OPF) presents a rare genetically caused osteopenia manifested by calcification and ossification of muscles, tendons, ligaments, fascia, and subcutaneous tissues due to aggressive fibroblasts proliferation.
N. A. Kovalenko-Klychkova, I. Y. Klychkova, V. M. Kenis, E. V. Melchenko   +3 more
doaj  

Plantar Pressure and Contact Area Measurement of Foot Abnormalities in Stroke Rehabilitation. [PDF]

Brain Sci, 2021
Rusu L, Paun E, Marin MI, Hemanth J, Rusu MR, Calina ML, Bacanoiu MV, Danoiu M, Danciulescu D.   +8 more
europepmc   +1 more source

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

Advanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini, Margalida Campaner Socias, Andreas Dimopoulos, Lorenza Rinvenuto, Enrico Pozzo, Diana Stalkopf, Angelo Serafini, Sara Morri, Ashley Wang, Rita La Rovere, Yoke Chin Chai, Sveva Bollini, Geert Bultynck, H. Llewelyn Roderick, Ioannis Papantoniou, Maurilio Sampaolesi   +15 more
wiley   +1 more source

Unveiling hidden challenges: impaired foot posture due to skin involvement in systemic sclerosis

Central Asian Journal of Medical Hypotheses and Ethics
Systemic sclerosis [SSc] is a chronic autoimmune disease characterized by fibrosis, vasculopathy, and immune dysregulation, primarily affecting the skin and various internal organs.
N. Gokcen
doaj   +1 more source

Gait Analysis Technologies for Evaluating Biomechanical Deviations: Insights from a Pilot Study on Healthy Athletes and Foot Deformities [PDF]

Balneo and PRM Research Journal
Gait analysis is an essential tool for assessing musculoskeletal function and identifying biomechanical abnormalities. This study aimed to establish normative reference values for gait parameters in young, physically active individuals and to identify ...
Elena Taina Avramescu, Anca Maria Amzolini, Ana Maria Bumbea, Simona Patru, Magdalena Rodica Traistaru, Carmen Daniela Neagoe, Gheorghe Ionescu, Constantin Munteanu, Daniela Matei   +8 more
doaj   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Functional Rehabilitation of a Neglected Foot Deformity: An Interesting Case Report

Indian Journal of Physical Medicine & Rehabilitation
Equinocavovarus deformity is the most common foot and ankle deformity in patients suffering from Post Polio Residual Paralysis (PPRP). These deformities can lead to gait abnormalities, abnormal pressure areas, increased energy expenditure and joint ...
Suman Badhal, Annie Mathew
doaj   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

Meeting the challenge for foot health in rheumatic diseases [PDF]

, 2004
Background: National guidelines recommend that patients with rheumatic diseases should have access to podiatry services and evidence is emerging that podiatry interventions are effective in the management of foot problems in this patient group.
Bowden, AP, Williams, AE
core   +1 more source