Results 321 to 330 of about 282,737 (397)

Definition and Classification of Dystonia

Movement Disorders, EarlyView.
Abstract Dystonia is a movement disorder with varied clinical features and diverse etiologies. Here we present a revision of the 2013 consensus definition and classification of dystonia in light of subsequent publications and experience with its application during the last decade.
Alberto Albanese, Kailash P. Bhatia, Victor S.C. Fung, Mark Hallett, Joseph Jankovic, Christine Klein, Joachim K. Krauss, Anthony E. Lang, Jonathan W. Mink, Sanjay Pandey, Jan K. Teller, Marina A.J. Tijssen, Marie Vidailhet, H.A. Jinnah   +13 more
wiley   +1 more source

Effects of temperature and environmental covariates on the dynamic transmission of hand, foot, and mouth disease in Zhejiang, China. [PDF]

PLoS Negl Trop Dis
Wen W, Miao Z, Zheng D, Ling F, Qian ZM, de Foy B, Howard SW, Sun J, Lin H.   +8 more
europepmc   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

Medicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury, Terin D'Amico, Brian S. J. Blagg   +2 more
wiley   +1 more source

Foot-and-mouth disease dynamics in multi-species livestock systems at the interface of African protected areas. [PDF]

Vet Res
Ploquin O, Grosbois V, Ndlovu M, Ndozore S, Munzamba M, Porovha E, Nkomo K, Basso O, Corbel G, Shumba R, Mhlanga MD, Mwandirigana E, Musekiwa B, Takayindisa E, Loisier A, Fritz H, Liégeois F, Caron A, Prugnolle F, Miguel E.   +19 more
europepmc   +1 more source

Identification and Biological Characterization of a Novel NRF2 Activator Molecule Released From the Membranes of Heat‐Treated Bifidobacterium breve NCC 2950

Molecular Nutrition &Food Research, EarlyView.
We have shed light on the mode of action behind the postbiotic form of Bifidobacterium breve NCC 2950. Heat treatment of this strain at 90°C leads to the production of 4‐oxo‐2‐pentenoic acid (OPA), which activates NRF2 host response, improving oxidative stress resistance and decreasing inflammation. ABSTRACT Postbiotics are defined as a “preparation of
Francis Foata, Stéphane Duboux, Sébastien Herzig, Federico Sizzano, Jonathan Thevenet, Philippe Guy, Serge Rezzi, Sylviane Métairon, Bertrand Bourqui, Ivan Montoliu, Annick Mercenier, Nabil Bosco   +11 more
wiley   +1 more source

Comparative Transcriptomics Analysis of Foot-and-Mouth Disease Virus-Infected Cell Model Systems. [PDF]

Vet Sci
Ma H, Zheng Z, Liu M, Zhang M, Qu X, Ren J, Liao M.   +6 more
europepmc   +1 more source

Safety Extension Study of Edaravone Oral Suspension in Patients With Amyotrophic Lateral Sclerosis for up to an Additional 96 Weeks of Treatment

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Edaravone intravenous (IV) and oral suspension have been shown to have similar pharmacokinetics, safety, and slowing of functional decline in patients with amyotrophic lateral sclerosis (ALS). Study MT‐1186‐A01 indicated that edaravone oral suspension was well‐tolerated over 48 weeks, with no new safety concerns identified ...
Angela Genge, Gary L. Pattee, Gen Sobue, Masashi Aoki, Hiide Yoshino, Philippe Couratier, Christian Lunetta, Susanne Petri, Daniel Selness, Vesna Todorovic, Nissim Sasson, Manabu Hirai, Fumihiro Takahashi, Alejandro Salah, Stephen Apple, Art Wamil, Alexander Kalin, Carlayne E. Jackson   +17 more
wiley   +1 more source

MARCH8 promotes the proteasomal degradation of foot-and-mouth disease virus VP1, VP2, and VP3 to negatively regulate viral replication. [PDF]

Vet Res
Yin M, Li X, Zhang M, Zhao Q, Wang H, Zhang H, Lu Z, Qian P.   +7 more
europepmc   +1 more source

Intratracheal Administration of Nanoplastics With Varying Surface Hydrophobicity Results in Coarsely Vacuolated Alveolar Macrophages, Transient Respiratory Inflammation, and Mild Collagen Deposition

Nano Select, EarlyView.
Nanoplastic hydrophobicity drives adverse effects in the lung. Single intratracheal administration of poly(vinyl acetate‐co‐alcohol) nanoplastics with varying surface hydrophobicity shows that the more hydrophobic nanoplastics increase prevalence of coarsely vacuolated alveolar macrophages, induce transient respiratory inflammation and mild collagen ...
Anna Babin Morgan, Yanira Riffo‐Vasquez, Aateka Bodhaniya, Stuart A. Jones, Ben Forbes, Kavitha Sunassee, Rafael T. M. de Rosales, Stephanie Wright, Clive Page, Lea Ann Dailey   +9 more
wiley   +1 more source

Emergency response for recently isolated Foot and Mouth Disease virus type A Africa in Egypt 2022. [PDF]

Sci Rep
Abousenna MS, Khafagy HA, Mohamed AAEM, El Sawy SEA, Shasha FAEM, Darwish DM, Shafik NG.   +6 more
europepmc   +1 more source