Results 151 to 160 of about 8,769 (269)

Social and Anxiety‐Like Behaviors Are Affected in Juvenile Mice With Gli2+/− but Not Gli3+/𝛥699 Genetic Modifications

Brain and Behavior, Volume 16, Issue 6, June 2026.
Across Gli3+/Δ699, Gli2+/−, and combined Gli2+/−;Gli3+/Δ699 mice (males and females, with wild‐type controls), GLI2 and GLI3 differentially regulate anogenital distance and juvenile behavior, with amplified effects under combined disruption, whereas circulating steroids and sexually dimorphic nucleus area remain unchanged. Created in BioRender. Niepsuj,
Thomas Niepsuj, Rithika Nurani, Leykza Carreras‐Simons, Wade Bushman, Joan S. Jorgensen, Walid A. Farhat, Anthony P. Auger   +6 more
wiley   +1 more source

Prenatal Diagnosis of Short Rib‐Polydactyly Syndrome (SRPS), DYNC2I1‐Related: Identification of a Novel Homozygous Missense Variant by Clinical Exome Sequencing

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Short rib‐polydactyly syndrome (SRPS), with or without polydactyly, encompasses a range of autosomal recessive skeletal dysplasias characterized by shortened limbs, narrow thorax, and visceral abnormalities. Accurate genetic testing is crucial for the diagnosis and treatment of different clinical subtypes. This study investigates gene variants
Shiyao Xian, Qi Zhao, Yanfang Li, Lihua Li, Zhongwei Li, Miaolian Zhang, Suihua Feng, Qiang Zhao   +7 more
wiley   +1 more source

Foot and Ankle Deformities in Fibular Hemimelia: Narrative Review. [PDF]

Orthop Rev (Pavia)
AlShayhan F.
europepmc   +1 more source

The Burden of Lower Limb Deformities in Low- and Lower-Middle-Income Countries: A Scoping Review. [PDF]

J Pediatr Soc North Am
Montoya RL, Agoro KS, Jodah R, Sabharwal S, Sabatini CS.   +4 more
europepmc   +1 more source

Management of Lower-Extremity Deformity in Arthrogryposis Multiplex Congentia: A Narrative Review. [PDF]

Med Sci Monit
Shang Y, Xu J.
europepmc   +1 more source

Reconstructive Surgery for Foot Ectrodactyly in an Adolescent Patient: A Case Report. [PDF]

J Orthop Case Rep
Meceda CJS, Tablante AJC, Tablante EB.
europepmc   +1 more source

Adverse outcomes among pregnant women with COVID‐19 according to hospitalization status: A prospective individual participant data meta‐analysis in Europe and North America

International Journal of Gynecology &Obstetrics, Volume 173, Issue 3, Page 1197-1206, June 2026.
Abstract Background Understanding the varied impact of COVID‐19 severity on pregnancy outcomes is crucial for informed clinical management and targeted interventions. Objective To evaluate the impact of COVID‐19 on pregnancy outcomes, distinguishing between pregnant women managed in primary care and those requiring hospitalization.
Odette de Bruin, Emeline Maisonneuve, Eimir Hurley, Hedvig M. E. Nordeng, Anick Bérard, Odile Sheehy, Padma Kaul, Mayura U. Shinde, Austin Cosgrove, Jennifer G. Lyons, Elizabeth Messenger‐Jones, Maria E. Kempner, Sengwee Toh, Wei Hua, José J. Hernández‐Muñoz, Leyla Sahin, Carolyn E. Cesta, David Hägg, Rosa Gini, Olga Paoletti, Beatriz Poblador‐Plou, Sue Jordan, Clara L. Rodríguez‐Bernal, Francisco Sánchez‐Sáez, Régis Lassalle, Marie‐Agnès Bernard, Fariba Ahmadizar, Guillaume Favre, Alice Panchaud, Kitty W. M. Bloemenkamp, Kelly Plueschke, Corinne de Vries, Satu J. Siiskonen, Miriam C. J. M. Sturkenboom, on behalf of the CONSIGN Collaboration Group, Benjamin P. Geisler, Mark Walker, Steven Hawken, Sasha Bernatsky, Sherif Eltonsy, Emma Hoffman, Andrew B. Petrone, Jolene Mosley, Jenice Ko, Claudia Bartolini, Giuseppe Roberto, Giorgio Limoncella, Anna Girardi, Giulia Hyeraci, Antonio Gimeno‐Miguel, Jonás Carmona‐Pírez, Antonio Poncel‐Falcó, Aida Moreno‐Juste, Alexandra Prados‐Torres, Daniel Thayer, Ian Farr, Saira Ahmed, Ieuan Scanlon, Gabriel Sanfélix‐Gimeno, Isabel Hurtado, Anibal Garcia‐Sempere, Salvador Peiro, Jérémy Jové, Dunia Sakr, Cécile Droz‐Perroteau, Ema Alsina, David Baud, Hilde M. Engjom, Judit Riera‐Arnau, Mònica Sabaté Gallego, Elena Ballarín Alins, Cristina Aguilera Martin, Melissa Kampman, Celline Brasil   +73 more
wiley   +1 more source

Clinical Variability Within the <i>PLOD2</i>-Associated Phenotypic Continuum: Three Novel Variants in Four Patients from a Descriptive Case Series. [PDF]

Genes (Basel)
Merkuryeva ES, Melnik EA, Kenis VM, Trofimova SI, Agranovich OE, Buklemishev YV, Rustamov KK, Chistol DV, Nagornova TS, Zabnenkova VV, Markova TV.   +10 more
europepmc   +1 more source

The complete Subtalar Release CSTR procedure for the surgical treatment of congenital clubfoot deformites

Acta Orthopaedica et Traumatologica Turcica
We have evaluted and discussed the 1 year foolow up of Complete Subtalar Release Procedure we have performed, for 16 Congenital Clup Foot Deformities of 11 children, in University of Istanbul Medical Faculty, Orthopaedics and Traumatology Departmant ...
Azmi Hamzaoglu, Fehmi Daldal, Onder Yazicioglu, Ayhan Aritamur, Yener Temelli   +4 more
doaj  

A c.89G>C p.(Gly30Ala) Variant in the DHCR7 Gene as a Cause of a Mild Phenotype in the Smith‐Lemli‐Opitz Syndrome

Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.
Smith‐Lemli‐Opitz syndrome (SLOS) is an autosomal recessive disorder caused by pathogenic variants in the DHCR7 gene. Based on our observations and a review of the literature, we demonstrate that the NM_001360.2(DHCR7):c.89G>C p.(Gly30Ala) variant is associated with a mild SLOS phenotype.
Júlia Martinková, Emílie Vyhnálková, Martin Schwarz, Miroslava Balaščaková, Veronika Biddle, Romana Borská, Lenka Fajkusová, Lukáš Ryba, Anna Křepelová   +8 more
wiley   +1 more source