Results 41 to 50 of about 24,307 (292)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Efficacy of the Ponseti Technique in Correcting Clubfoot Deformity and Influence of Residual Deformity in Patient Reported Outcomes: A Prospective Comparative and Controlled Study

Foot & Ankle Orthopaedics, 2023
Category: Other; Hindfoot Introduction/Purpose: Clubfoot deformity (CFD) is one of the most common congenital deformities of the foot and ankle and is characterized by different severities of foot equinus, cavus, varus, and adduction.
Ryan Jasper, Jose Morcuende MD, Vineel Mallavarapu BS, Hannah J. Stebral BS, Kepler A.M. Carvalho MD, Nacime Salomao Barbachan Mansur MD, PhD, Grayson M. Talaski, Eli Schmidt, Kevin Dibbern PhD, Cesar de Cesar Netto MD, PhD   +9 more
doaj   +1 more source

Assessment of foot deformities in patients with type 2 diabetes mellitus

, 2023
Background: Affection of lower extremity in diabetic patients leads to development of several foot deformities. The knowledge so far about the particulars of foot deformity in diabetic population is limited.
Pandey, Ritesh A., Ritesh A. Pandey, Priyank Deepak   +2 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Foot deformities in diastrophic dysplasia. An analysis of 102 patients

, 1992
The exceptionally high prevalence of diastrophic dysplasia in Finland has enabled us to analyse the foot deformities of 102 patients at their first orthopaedic evaluation and classify 204 feet into five categories.
J Merikanto, M Poussa, I Kaitila, E Marttinen, S Ryoppy   +4 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Foot and Ankle Offset (FAO) Does Not Reflect the Actual Hindfoot Alignment in Cases Involving Ankle and/or Sagittal Foot and Ankle Deformities

Foot & Ankle Orthopaedics, 2022
Category: Hindfoot; Ankle; Midfoot/Forefoot Introduction/Purpose: The foot and ankle offset (FAO) was developed as a 3D biometric tool to measure hindfoot alignment on weightbearing CT (WBCT) scans.
Shuyuan Li MD, PhD, Sera Sempson BS, Wanjun Gu BS, BA, Chao Wang BS, Mingjie Zhu DAOM, MPH, Ming-Zhu Zhang MD, PhD, Kenneth J. Hunt MD, Mark S. Myerson MD   +7 more
doaj   +1 more source

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles, Hannah F. Brubeck, Adrienne D. Tanus, Courtney N. Loecker, Punyasha Roul, Bryant R. England, Elizabeth R. Wahl, James S. Andrews, Namrata Singh, Joshua F. Baker, Patricia P. Katz, Dolores M. Shoback, Jose M. Garcia, Ariela R. Orkaby, Katherine D. Wysham   +14 more
wiley   +1 more source

Frequency of foot deformity in preschool girls [PDF]

Vojnosanitetski Pregled, 2010
Background/Aim. In order to determine the moment of creation of postural disorders, regardless of the causes of this problem, it is necessary to examine the moment of entry of children into a new environment, ie. in kindergarten or school.
Mihajlović Ilona, Smajić Miroslav, Sente Jelena   +2 more
doaj   +1 more source

Risk Factors for Diabetic Peripheral Neuropathy, Peripheral Artery Disease, and Foot Deformity Among the Population With Diabetes in Beijing, China: A Multicenter, Cross-Sectional Study

Frontiers in Endocrinology, 2022
Diabetic peripheral neuropathy (DPN), peripheral artery disease (PAD), and foot deformity are the most common causes of diabetic foot, which can considerably worsen the patient’s quality of life.
Jiayi Liu, Xiaoyong Yuan, Jin Liu, Geheng Yuan, Yalan Sun, Donghui Zhang, Xin Qi, Huijuan Li, Junqing Zhang, Bing Wen, Xiaohui Guo   +10 more
doaj   +1 more source