Results 191 to 200 of about 9,817,386 (374)

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

open access: yesAdvanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen   +5 more
wiley   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

open access: yesAdvanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh   +3 more
wiley   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires   +4 more
wiley   +1 more source

Laser‐Induced Graphene‐Assisted Patterning and Transfer of Silver Nanowires for Ultra‐Conformal Breathable Epidermal Electrodes in Long‐Term Electrophysiological Monitoring

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a novel method using laser‐induced graphene (LIG) to enable high‐yield transfer of silver nanowire (AgNW) networks onto ultra‐low modulus, breathable silicone substrates. This approach creates ultra‐conformal epidermal electrodes (≈50 µm) for long‐term, high‐fidelity electrophysiological monitoring, even in challenging conditions ...
Jiuqiang Li   +10 more
wiley   +1 more source

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