Results 191 to 200 of about 186,373 (252)

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Intervention of pharmaceutical care on the quality-adjusted life years in diabetic foot ulcer patients-A randomized controlled study. [PDF]

J Educ Health Promot
Raju BN, Mateti UV, Mohan R, D'Souza C, D'Souza N.   +4 more
europepmc   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Development and Validation of an Algorithm to Objectively Quantify Adherence to Offloading Interventions. [PDF]

J Foot Ankle Res
Yalla SV, Jhaveri SN, Negron-Fernandez NS, Crews RT, Rosenblatt NJ.   +4 more
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Gait Biomechanics Across BMI Categories in Adults: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
García-Gomariz C, Andrés-Reig S, Chiva-Miralles MJ, Painceira-Villar R, Blasco JM.   +4 more
europepmc   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

Case Report: Progressive limb necrosis as a portal to multifocal osteomyelitis in pediatric septic shock: a tissue-oriented management paradigm. [PDF]

Front Pediatr
Yang C, Zhou W, Huang X, Li J.
europepmc   +1 more source

Integrated Opto–Biomechatronics For Single Muscle Fibre Structure‐Function Assessment: The MyoRobot 3.0

Advanced Science, EarlyView.
We present the MyoRobot 3.0, an advanced platform that combines high‐resolution imaging with automated mechanical testing to improve the accuracy of single muscle fibre analysis. The system tracks fibre diameter changes during stretch, preventing major stress miscalculations.
Michael Haug, Moritz Hellmann, Larysa Kovbasyuk, Maria Eleni Vazakidou, Milena Theis, Oliver Friedrich   +5 more
wiley   +1 more source

Risk Factors Associated With Methicillin-Resistant <i>Staphylococcus aureus</i> Infections in Patients With Diabetic Foot Ulcers in Tehran. [PDF]

Can J Infect Dis Med Microbiol
Khalili H, Mahrooghi M, Najar-Peerayeh S, Alamdary SZ, Sepas HN, Bakhshi B.   +5 more
europepmc   +1 more source