Results 221 to 230 of about 517,971 (261)

Editorial: Advancing bone and soft tissue repair: bioengineering from cellular insights to clinical applications. [PDF]

Front Cell Dev Biol
Li YX, Zhao LM, Zhang H.
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Clinical Utility of Small Extracellular Vesicles as Liquid Biopsy for Oral Mucosal Disease Diagnostics: Emerging Perspectives. [PDF]

Diagnostics (Basel)
Adebayo OF, Temilola DO, Owotade FJ, Chetty M.   +3 more
europepmc   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

'No Foot, No Future': Lived Experiences of Foot Health and Care Access Among Rough-Sleeping Adults in a UK Coastal Community-A Qualitative Study. [PDF]

J Foot Ankle Res
Bower J, Paton J.
europepmc   +1 more source

Characterization of T cell responses against <i>Fusobacterium necrophorum</i> naturally-induced foot rot in dairy cows. [PDF]

Front Immunol
Yang Y, Zhang L, Yu C, Zhang S, Ye C, Yang Z, Zhang Z.   +6 more
europepmc   +1 more source

Behavioral Sciences Training Applications of a Computerized Student-Patient Encounter Log System [PDF]

, 2003
Morewitz, Stephen J., Shaw, G.
core   +1 more source

Editorial: Innovative therapeutic strategies for managing diabetic foot ulcers and mitigating associated complications. [PDF]

Front Pharmacol
Omolo CA, Yata VK, Janapati YK, Dachani SR.   +3 more
europepmc   +1 more source