Results 91 to 100 of about 12,243,471 (240)

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu   +10 more
wiley   +1 more source

An In-Shoe Laser Doppler Sensor for Assessing Plantar Blood Flow in the Diabetic Foot [PDF]

open access: yes
An in-shoe laser Doppler sensor for assessing plantar blood flow in the diabetic foot. Jonathan Edwin Cobb Plantar ulceration is a complication of the diabetic foot prevalent in adults with type 11 diabetes mellitus.
Cobb, Jonathan E.
core   +4 more sources

Basics of Ankle Arthroscopy Part 3: Patient Positioning and Preparation for Posterior Ankle Arthroscopy

open access: yesArthroscopy Techniques
Ankle arthroscopy is an important diagnostic and therapeutic tool in the treatment of pathologies of the posterior ankle joint. In a series of 7 articles, the basics of ankle arthroscopy are reviewed. In this Technical Note (Part 3), patient positioning,
James J. Butler, M.B., B.Ch.   +7 more
doaj   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph   +5 more
wiley   +1 more source

A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy. We identified a novel KCNA1 variant (A401T) in a 16‐year‐old patient with autism spectrum disorder, borderline intellectual disability, and tremor, without episodic ataxia or epilepsy ...
Juan Darío Ortigoza‐Escobar   +7 more
wiley   +1 more source

Shoes and foot health \nShoes and foot health

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Bearing the body weight, our feet have an important function in the entirety of the musculoskeletal system. In this article, in order to have more healthy feet, specialties which must be met in normal shoes and various shoes for the treatment of ...
Veli Lok, Hilmi C. Aydinok
doaj  

Ofatumumab Therapy and Long‐Term Seizure Outcomes of Patients With Relapsing Anti‐NMDA Receptor Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There is a lack of studies on seizure outcomes associated with ofatumumab therapy in patients for relapsing anti‐N‐methyl‐D‐aspartate (NMDA) receptor encephalitis. We aimed to evaluate long‐term seizure outcomes of ofatumumab therapy for relapsing anti‐NMDA receptor encephalitis.
Jian Wang, Mengjiao Li, Ping Kong
wiley   +1 more source

Basics of Ankle Arthroscopy Part 5: Posterior Tibial Tendoscopy: Surface Anatomy, Portal Placement, and Diagnostic Evaluation

open access: yesArthroscopy Techniques
Posterior tibial tendoscopy is an important diagnostic and therapeutic tool in the treatment of disorders of the posterior tibial tendon. In this article, the relevant surface anatomy, portal placement, and diagnostic tendoscopy are reviewed.
James J. Butler, M.B., B.Ch.   +6 more
doaj   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli   +10 more
wiley   +1 more source

Basics of Ankle Arthroscopy Part 7: Achilles Tendoscopy: Surface Anatomy, Portal Placement, and Diagnostic Evaluation

open access: yesArthroscopy Techniques
Achilles tendoscopy is an important diagnostic and therapeutic tool in the treatment of pathologies of the Achilles tendon. In this article, the basics of Achilles tendoscopy are reviewed, including the relevant surface anatomy, portal placement, and ...
James J. Butler, M.B., B.Ch.   +5 more
doaj   +1 more source

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