Results 41 to 50 of about 144,067 (258)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

The influence of pain exacerbation on rear foot eversion and plantar pressure symmetry in women with patellofemoral pain: a cross sectional study

BMC Musculoskeletal Disorders
Background The patellofemoral joint (PFJ) stress as a primary mechanical stimulus in the patellofemoral pain (PFP) etiology is affected by plantar pressure symmetry.
Ali Yalfani, Fatemeh Ahadi, Mohamadreza Ahmadi   +2 more
doaj   +1 more source

Footstep-induced energy harvesting through piezoelectric-embedded insoles

Cogent Engineering
The effectiveness of piezoelectric footwear depends on accurately identifying the areas of the shoe that experience the greatest pressure during walking or running.
Li Wah Thong, Robin Tan, Sin Ting Lim, Fahmidul Huq Syed, Sharmeeni Murugan   +4 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Foot segments mobility and plantar pressure in the normal foot [PDF]

Journal of Foot and Ankle Research, 2014
Background The foot is generally regarded as a flexible structure which can adjust its flexibility in response to variable dynamic conditions in different phases within different motor tasks. In gait, both kinematics and baropodometry have shown to be affected by functional and structural factors [1].
Paolo Caravaggi, Claudia Giacomozzi, Alberto Leardini   +2 more
openaire   +2 more sources

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Predicted sewing thread consumption using neural network method based on the physical and structural parameters of knitted fabrics

AUTEX Research Journal
This article presents an experimental study on the influence of various parameters on sewing thread consumption. Four knitted samples, featuring different structures and thicknesses, were tested by sewing two- and three-layer using chain stitch type 401.
Khedher Faouzi, Hamdi Thouraya, Jaouachi Boubaker, Jmali Mohamed   +3 more
doaj   +1 more source

The relationships between foot arch volumes and dynamic plantar pressure during midstance of walking in preschool children. [PDF]

PLoS ONE, 2014
OBJECTIVES: The purpose of this study was to examine the correlation between the foot arch volume measured from static positions and the plantar pressure distribution during walking. METHODS: A total of 27 children, two to six years of age, were included
Hsun-Wen Chang, Hsiao-Feng Chieh, Chien-Ju Lin, Fong-Chin Su, Ming-June Tsai   +4 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source