Results 51 to 60 of about 2,860,879 (239)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Advanced Foot Pressure Technology for Demonstrating the Influence of Over-weight and Obesity on Ankle Joint [PDF]

, 2019
Foot pressure technology has been utilized to study the influence of over-weight and obesity on the ankle joint which because of gaining weight lead to change gait characteristics, particularly foot ailments, and has been used in academic teaching in the
Albert K. Chong, Al-Magsoosi, Suhad K.R, Chong, Albert K., Suhad K.R Al-Magsoosi   +3 more
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

An In-Shoe Laser Doppler Sensor for Assessing Plantar Blood Flow in the Diabetic Foot [PDF]

An in-shoe laser Doppler sensor for assessing plantar blood flow in the diabetic foot. Jonathan Edwin Cobb Plantar ulceration is a complication of the diabetic foot prevalent in adults with type 11 diabetes mellitus.
Cobb, Jonathan E.
core   +5 more sources

The influence of pain exacerbation on rear foot eversion and plantar pressure symmetry in women with patellofemoral pain: a cross sectional study

BMC Musculoskeletal Disorders
Background The patellofemoral joint (PFJ) stress as a primary mechanical stimulus in the patellofemoral pain (PFP) etiology is affected by plantar pressure symmetry.
Ali Yalfani, Fatemeh Ahadi, Mohamadreza Ahmadi   +2 more
doaj   +1 more source

Detection of freezing of gait in Parkinson's disease from foot-pressure sensing insoles using a temporal convolutional neural network

Frontiers in Aging Neuroscience
BackgroundsFreezing of gait (FoG) is a common and debilitating symptom of Parkinson's disease (PD) that can lead to falls and reduced quality of life.
Jae-Min Park, Chang-Won Moon, Chang-Won Moon, Byung Chan Lee, Eungseok Oh, Juhyun Lee, Won-Jun Jang, Kang Hee Cho, Kang Hee Cho, Si-Hyeon Lee   +9 more
doaj   +1 more source

Comparison of the Plantar Pressure and Foot Function and Range of Motion in Distance Runners With the Normal, Pronated, and Supinated Feet During Static Standing

Journal of Modern Rehabilitation, 2020
Introduction: This study aimed to investigate the foot function, range of motion, plantar pressure, and plantar contact area in the distance runners with normal, pronated, highly-pronated, supinated, and highly-supinated foot posture groups during static
Navid Keivanfar, Azadeh Shadmehr, Khadijeh Otadi, Seyed Mohsen Mir, Saman Salehi   +4 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Foot segments mobility and plantar pressure in the normal foot [PDF]

Journal of Foot and Ankle Research, 2014
Background The foot is generally regarded as a flexible structure which can adjust its flexibility in response to variable dynamic conditions in different phases within different motor tasks. In gait, both kinematics and baropodometry have shown to be affected by functional and structural factors [1].
Paolo Caravaggi, Claudia Giacomozzi, Alberto Leardini   +2 more
openaire   +2 more sources

The impact of rheumatoid arthritis on foot function in the early stages of disease: a clinical case series [PDF]

, 2006
BACKGROUND Foot involvement occurs early in rheumatoid arthritis but the extent to which this impacts on the structure and function leading to impairment and foot related disability is unknown. The purpose of this study was to compare clinical disease
Helliwell, Philip S., Woodburn, James, James Woodburn, Woodburn, J., Paul Emery, Emery Paul, Helliwell Philip S, Turner Deborah E, Turner, D.E., Turner, Deborah E., Deborah E Turner, Helliwell, P.S., Emery, P., Philip S Helliwell, Woodburn James, Emery, Paul   +15 more
core   +2 more sources