Results 111 to 120 of about 2,711,818 (230)

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Disease knowledge in patients attending a diabetic foot clinic

, 2005
Background: Foot-specific patient education is an essential element of a health system diabetic foot program. Foot-specific patient education must be individualized, because of cognitive deficits in individuals with long-standing diabetes.
Batista, Fabio [UNIFESP], Pinzur, Michael S., Fabio Batista, Michael S. Pinzur   +3 more
core   +1 more source

Effect of the Dynamic Orthotic Garment on Postural Control, and Endurance in Children with Spastic Diplegic Cerebral Palsy: A Randomized Controlled Trial

Journal of Multidisciplinary Healthcare
Hatem A Emara,1,2,* Ahmed H Al-Johany,3 Osama A Khaled,1,4 Abdullah M Al-Shenqiti,1 Abdul Rahman H Ali,5 Marwan M Aljohani,1 Eman Sobh6,7,* 1Physical Therapy Department, College of Medical Rehabilitation Sciences, Taibah University, Medina, Saudi
Emara HA, Al-Johany AH, Khaled OA, Al-Shenqiti AM, Ali ARH, Aljohani MM, Sobh E   +6 more
doaj  

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Hydrogel‐Based 3D‐Printed Anthropomorphic Breast Phantom for Emulating Mechanical and Dielectric Properties of Mammary Tissue. Applications in Microwave Imaging

Advanced Functional Materials, EarlyView.
A 3D‐printable breast phantom is developed using patient‐derived MRI data and hydrogels that replicate the dielectric properties of healthy and cancerous tissues. Mechanical and dielectric characterization confirm its suitability for microwave imaging.
Carlos M. Andreu, Daniel Álvarez Sánchez‐Bayuela, Gianluigi Tiberi, Eliana Canicattì, Agostino Monorchio, Ester Vázquez   +5 more
wiley   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

The Effect of Different Types of Foot Orthoses on Foot Plantar Pressure in Subjects with Plantar Fasciitis: A Literature Review

Journal of Rehabilitation, 2019
Objective Plantar fasciitis is a plantar fascia inflammation and one of the most common causes of heel pain, causing pain in the inner side of the heel bone.
Elahe Karami, Aliyeh Daryabor, Reza Vahab Kashani, Monireh Ahmadi Bani   +3 more
doaj  

Deep‐learning enabled smart insole system aiming for multifunctional foot‐healthcare applications

Exploration
Real‐time foot pressure monitoring using wearable smart systems, with comprehensive foot health monitoring and analysis, can enhance quality of life and prevent foot‐related diseases.
Yu Tian, Lei Zhang, Chi Zhang, Bo Bao, Qingtong Li, Longfei Wang, Zhenqiang Song, Dachao Li   +7 more
doaj   +1 more source

Synergistic Integration of Liquid Crystalline Ordering and Dynamic Networks for Ultrarobust Bismaleimide Vitrimers

Advanced Functional Materials, EarlyView.
A liquid‐crystalline bismaleimide vitrimer integrates local mesogenic organization with exchange‐active ester connectivity, achieving a glass‐transition temperature near 300°C while remaining reprocessable. Stress‐relaxation analysis and temperature‐dependent remolding reveal how segmental mobility, network rearrangement, and structural integrity ...
Woohyeon Kwon, Van‐Kien Hoang, Kyosun Ku, Hyeonuk Yeo   +3 more
wiley   +1 more source

Electron‐Deficient Linkers Enhance H2O2 Electrosynthesis in Covalent Organic Frameworks

Advanced Functional Materials, EarlyView.
Linker π‐conjugation modulates the electronic state of the Ni–N4 centers and their interaction with the key *OOH intermediate while preserving the primary coordination motif. NiPc‐PTDA delivers an H2O2 selectivity of 92% and a production rate of 34.8 mol gcat−1 h−1, highlighting linker electronic properties as a molecular design parameter for NiPc ...
Houting Xie, Rui Guo, Zhen Liu, Yang Hu, Laichun Zhao, Omid Mazaheri, Bufeng Zhang, Shuaijun Pan   +7 more
wiley   +1 more source