Results 31 to 40 of about 141,308 (258)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Plantar pressure distribution profile of type 2 diabetes mellitus with diabetic foot syndrome: A hospital-based observational study

open access: yesСахарный диабет, 2022
INTRODUCTION: The prevalence of diabetic foot syndrome is increasing in the Indian population. It is a triad of neurological, vascular, and biomechanical changes due to long term diabetes mellitus (DM).
H. Ya. Korada   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Predicted sewing thread consumption using neural network method based on the physical and structural parameters of knitted fabrics

open access: yesAUTEX Research Journal
This article presents an experimental study on the influence of various parameters on sewing thread consumption. Four knitted samples, featuring different structures and thicknesses, were tested by sewing two- and three-layer using chain stitch type 401.
Khedher Faouzi   +3 more
doaj   +1 more source

Plantar Pressure Detection with Fiber Bragg Gratings Sensing System

open access: yesSensors, 2016
In this paper, a novel fiber-optic sensing system based on fiber Bragg gratings (FBGs) to measure foot plantar pressure is proposed. This study first explores the Pedar-X insole foot pressure types of the adult-size chart and then defines six measurement
Tsair-Chun Liang   +2 more
doaj   +1 more source

Diabetic foot or pressure ulcer on the foot? [PDF]

open access: yes, 2011
Diabetes is one of the greatest health challenges facing the United Kingdom (UK) today, with 2.5 million people diagnosed with diabetes in the UK, not including up to half a million people who have the condition but are unaware of it (Diabetes UK, 2009).
Ousey, Karen   +2 more
openaire  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CLINICAL EXAMINATION AND FOOT PRESSURE ANALYSIS OF DIABETIC FOOT: PROSPECTIVE ANALYTICAL STUDY IN INDIAN DIABETIC PATIENTS

open access: yesNational Journal of Medical Research, 2016
Aim: Clinical examination of diabetic foot to find out its pathological Complications and analysis of plantar foot pressure of diabetic foot patients in Indian population. Method: This was prospective analytical study in Indian diabetic patients. 102
Harshanand J Popalwar   +3 more
doaj  

Outcomes and potential mechanism of a protocol to optimize foot orthoses in patients with rheumatoid arthritis

open access: yesBMC Musculoskeletal Disorders, 2020
Background Foot problems are highly prevalent in patients with rheumatoid arthritis. Treatment of foot problems related to rheumatoid arthritis often consists of custom made foot orthoses.
Marloes Tenten-Diepenmaat   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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