Results 31 to 40 of about 2,917,034 (236)

The Thermo-Pressure Concept: A New Model in Diabetic Foot Risk Stratification

Applied Sciences, 2021
Elevated foot pressure and high temperatures have been proposed as predictive factors for diabetic foot ulceration; however, on their own, their predictive value is still questionable.
Sarah Perren, Cynthia Formosa, Liberato Camilleri, Nachiappan Chockalingam, Alfred Gatt   +4 more
doaj   +1 more source

Outcomes and potential mechanism of a protocol to optimize foot orthoses in patients with rheumatoid arthritis

BMC Musculoskeletal Disorders, 2020
Background Foot problems are highly prevalent in patients with rheumatoid arthritis. Treatment of foot problems related to rheumatoid arthritis often consists of custom made foot orthoses.
Marloes Tenten-Diepenmaat, Joost Dekker, Jos W. R. Twisk, Elleke Huijbrechts, Leo D. Roorda, Marike van der Leeden   +5 more
doaj   +1 more source

Predicting the metabolic cost of exoskeleton-assisted squatting using foot pressure features and machine learning

Frontiers in Robotics and AI, 2023
Introduction: Recent studies found that wearable exoskeletons can reduce physical effort and fatigue during squatting. In particular, subject-specific assistance helped to significantly reduce physical effort, shown by reduced metabolic cost, using human-
Sruthi Ramadurai, Heejin Jeong, Myunghee Kim   +2 more
doaj   +1 more source

Pressure of Fused Foot

Orthopedics & Traumatology, 1954
Author examined the human foot pressure in 51 cases of fused feet by means of oppress spur used dental modelling.The feet examined were operated by usual methods of arthrodesis. The preoperative deformities were classified into talipes calcaneus (7 cases), equinus (15 cases), varus (15 cases), planovalgus (one case) and flail feet (13 cases).By this ...
openaire   +3 more sources

Effect of the shoe on plantar foot pressures [PDF]

Acta Orthopaedica Scandinavica, 1995
The bare foot plantar pressures were compared to in-shoe pressure measurements in 11 normal male volunteers using the EMED system. Shoes diminished pressures and forces in most areas under the foot except the medial forefoot. The hallux showed less force, a smaller contact area and a reduced contact time. Therefore a shoe can interfere with the toe-off
M, Nyska, C, McCabe, K, Linge, P, Laing, L, Klenerman   +4 more
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Footstep-induced energy harvesting through piezoelectric-embedded insoles

Cogent Engineering
The effectiveness of piezoelectric footwear depends on accurately identifying the areas of the shoe that experience the greatest pressure during walking or running.
Li Wah Thong, Robin Tan, Sin Ting Lim, Fahmidul Huq Syed, Sharmeeni Murugan   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Forefoot pathology in rheumatoid arthritis identified with ultrasound may not localise to areas of highest pressure: cohort observations at baseline and twelve months [PDF]

, 2011
BackgroundPlantar pressures are commonly used as clinical measures, especially to determine optimum foot orthotic design. In rheumatoid arthritis (RA) high plantar foot pressures have been linked to metatarsophalangeal (MTP) joint radiological erosion ...
Lindsey Hooper, David Culliford, Gay Anita, Arden Nigel K, Nigel K Arden, Allen, Ruth, Edwards Christopher J, Ruth Allen, Edwards, Christopher J., Anita Gay, Culliford, David, Hooper, Lindsey, Hooper Lindsey, Burridge, Jane, Burridge Jane, Bowen Catherine J, James Beacroft, Bowen, Catherine J., Beacroft James, Catherine J Bowen, Beacroft, James, Gay, Anita, Christopher J Edwards, Allen Ruth, Jane Burridge, Culliford David, Arden, Nigel K.   +26 more
core   +2 more sources

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source