Results 151 to 160 of about 708,864 (357)

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

PERIPHERAL VASCULAR DISEASE IN DIABETIC FOOT ULCER

, 2018
Objective: To determine the frequency of peripheral vascular disease in diabetic foot ulcer. Patients and Methods: The cross sectional study of six months was conducted on type 2 diabetic population with foot ulcer > 35 year age and either gender ...
Dr. Tariq Zaffar Shaikh, Dr. Abdul Ghani Rahimoon, Dr. Faheem Ahmed Memon, Dr. Hamid Nawaz Ali Memon, Dr. Ali Raza Shaikh, Dr. Alveena Batool Syed, Dr. Samar Raza
core   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Diabetic foot ulcer and its surgical management

, 2019
Background: Almost 80% population of diabetic foot are from low to middle income countries like India, a country with second largest number of diabetic populations. Prevalence of diabetes mellitus in India is 9.3%.
Solanki, Pradip V., Dave, Jignesh P., Lakhani, Darshan J., Ramani, Jignesh K., Makadiya, Chirag R., Agrawal, Kartik K.   +5 more
core   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

DRD2 Dopamine Receptor and IL-1β Gene Expression Changes Involved in Wound Healing in Type 2 Diabetic Patients with Foot Ulcer

Journal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Diabetic foot ulcer is a complication of type 2 diabetes. Various factors, such as changes in the level of cytokines (especially IL-1β) can interfere with the development of diabetic foot ulcer. Several factors affect the level of
Neda Ebrahimzadeh, Hajar Vaseghi, Garshasb Rigi, Gholamreza Esmaeeli Djavid, Shahla Mohammad Ganji, Amirreza Farhoud, Majid Pornour   +6 more
doaj  

Construction of risk prediction model for recurrence of diabetic foot ulcer

Huli yanjiu, 2022
ObjectiveThis study aimed to investigate the current status and influencing factors of diabetic foot ulcer recurrence within 1 year after healing and to establish a risk prediction model.MethodsThe convenience sampling method was used to select patients ...
LYU Jing, YUAN Li, LI Rao, HUANG Fengmei
doaj  

A shift in priority in diabetic foot care and research: 75% of foot ulcers are preventable

, 2016
Diabetic foot ulceration poses a heavy burden on the patient and the healthcare system, but prevention thereof receives little attention. For every euro spent on ulcer prevention, ten are spent on ulcer healing, and for every randomized controlled trial ...
van Netten, Jaap J., Bus, Sicco A.
core   +1 more source

Fibroblasts in Diabetic Foot Ulcers

International Journal of Molecular Sciences
Fibroblasts are stromal cells ubiquitously distributed in the body of nearly every organ tissue. These cells were previously considered to be “passive cells”, solely responsible for ensuring the turnover of the extracellular matrix (ECM). However, their versatility, including their ability to switch phenotypes in response to tissue injury and dynamic ...
Francesca A. Voza, Carlos Theodore Huerta, Nga Le, Hongwei Shao, Antoine Ribieras, Yulexi Ortiz, Carl Atkinson, Tiago Machuca, Zhao-Jun Liu, Omaida C. Velazquez   +9 more
openaire   +2 more sources

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source