Results 101 to 110 of about 174,199 (337)

PERFECTION OF PRODUCTION TECHNOLOGY OF REBARS OF SMALL SECTIONS, ROLLED BY MULTISTRAND ROLLING-AND-SEPARATION

open access: yesЛитьë и металлургия, 2009
The expediency of application no driving universal mills for increase o f a production efficiency bars of hire with use of no conventional process mac rolling of rolling-division is shown.
S. M. Zhuchkov   +5 more
doaj  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Who gets to be an ELT course book author? Native speakerism in English for specific purposes and business English course books

open access: yesFrontiers in Education
IntroductionNative speakerism has a profound influence on many aspects of ELT, for example negatively affecting job opportunities of those perceived as ‘non-native speakers’.
Marek Kiczkowiak
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

What kind of support do firms prefer to hire apprentices in a recession?

open access: yesEmpirical Research in Vocational Education and Training
Apprenticeship training is strongly developed in Switzerland. During the Covid-19 pandemic, training firms however faced severe difficulties and many decided not to (or were unable to) hire apprentices. To minimize negative consequences, authorities from
José V. Ramirez, Sylvain Weber
doaj   +1 more source

Home - About - Disclaimer - Privacy