Results 211 to 220 of about 174,199 (337)
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
It's not you, it's the government; Or, PrEPping pharmacists on supporting sexual health in underserved populations. [PDF]
Lam J.
europepmc +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
What PIs want when hiring a clinical research coordinator. [PDF]
Fisher E, Thomas R, Choi I, McCauley L.
europepmc +1 more source
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley +1 more source
The impact of the COVID-19 pandemic on students' views of a career in general practice: a focus group study. [PDF]
Hook Z+8 more
europepmc +1 more source
White Christian Nationalism in the Rural United States
ABSTRACT Many scholars have sought to link the rise of right‐wing populist movements, like White Christian Nationalism (WCN), to the impacts of political‐economic structural changes, such as globalization and financialization. Although these structural changes may explain some grievances, they do not explain why people express those grievances in the ...
Leland L. Glenna
wiley +1 more source
Social Workers' Reports on Needs and Recommendations to Enhance School Safety. [PDF]
Fensterstock N+16 more
europepmc +1 more source