Results 81 to 90 of about 228,070 (381)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Make Versus Buy in Trucking: Asset Ownership, Job Design and Information [PDF]

open access: yes
Explaining patterns of asset ownership in the economy is a central goal of both organizational economics and industrial organization. We develop a model of asset ownership in trucking, which we test by examining how the adoption of different classes of ...
George P. Baker, Thomas N. Hubbard
core  

Slow to Hire, Quick to Fire: Employment Dynamics with Asymmetric Responses to News

open access: yesJournal of Political Economy, 2014
Concave hiring rules imply that firms respond more to bad shocks than to good shocks. They provide a unified explanation for several seemingly unrelated facts about employment growth in macro- and microdata.
Cosmin L. Ilut   +2 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Regulation in the Taxi Industry. [PDF]

open access: yes, 1992
This paper examines some of the economic reasons for price and entry regulation in the taxi industry and presents the legal framework under which taxis and hire cars are regulated in England and Wales outside London. It is argued that the current law is
Toner, J.P.
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

The Thomas B. Fordham Foundation and Institute: Influence for Hire

open access: yesNonpartisan Education Review, 2018
no ...
Richard P. Phelps
doaj  

Behaviour of the main okra (Abelmoschus spp.) cultivars grown in Côte d’Ivoire to root-knot nematodes (Meloidogyne incognita (Kofoid and White, 1919)) under greenhouse conditions

open access: yesActa Agriculturae Slovenica
Root-knot nematodes are the main factor limiting okra production in Côte d’Ivoire. Using resistant cultivars appears to be one of the best strategies for managing root-knot nematodes.
Yadom Yao François Regis KOUAKOU   +5 more
doaj   +1 more source

Kenya’s emergency-hire nursing programme: a pilot evaluation of health service delivery in two districts

open access: yesHuman Resources for Health, 2014
ObjectiveTo assess the feasibility of utilizing a small-scale, low-cost, pilot evaluation in assessing the short-term impact of Kenya’s emergency-hire nursing programme (EHP) on the delivery of health services (outpatient visits and maternal-child health
S. Vindigni   +11 more
semanticscholar   +1 more source

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