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Practical Neurology, 2020 Patent foramen ovale (PFO) is the most common anatomical cause of an interatrial shunt. It is usually asymptomatic but may cause paradoxical embolism, manifesting as stroke, myocardial infarction or visceral/peripheral ischaemia. PFO is a risk factor for stroke and may be associated with migraine with aura. New evidence suggests PFO closure reduces the
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Nature Reviews Disease Primers, 2016
Patent foramen ovale (PFO) is the most common congenital heart abnormality of fetal origin and is present in approximately ∼25% of the worldwide adult population. PFO is the consequence of failed closure of the foramen ovale, a normal structure that exists in the fetus to direct blood flow directly from the right to the left atrium, bypassing the ...
Karina W. Davidson +8 more
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Patent foramen ovale (PFO) is the most common congenital heart abnormality of fetal origin and is present in approximately ∼25% of the worldwide adult population. PFO is the consequence of failed closure of the foramen ovale, a normal structure that exists in the fetus to direct blood flow directly from the right to the left atrium, bypassing the ...
Karina W. Davidson +8 more
+9 more sources
Expert Review of Cardiovascular Therapy, 2005
Patent foramen ovale is incriminated in patients with cryptogenic stroke; however, concrete evidence that closure of patent foramen ovale using various devices is superior to continued medical therapy is not yet available. Controlled randomized trials are well underway to address this issue.
Yun-Ching Fu, Ziyad M. Hijazi
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Patent foramen ovale is incriminated in patients with cryptogenic stroke; however, concrete evidence that closure of patent foramen ovale using various devices is superior to continued medical therapy is not yet available. Controlled randomized trials are well underway to address this issue.
Yun-Ching Fu, Ziyad M. Hijazi
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Cardiology Clinics, 2013
Patent foramen ovale (PFO) is a common developmental anomaly that allows for the passage of blood and other substances from the venous to the arterial circulation. The study of PFO closure has been challenging due to widely available off-label closures performed outside the clinical trial setting.
Michael S. Kim +2 more
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Patent foramen ovale (PFO) is a common developmental anomaly that allows for the passage of blood and other substances from the venous to the arterial circulation. The study of PFO closure has been challenging due to widely available off-label closures performed outside the clinical trial setting.
Michael S. Kim +2 more
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Patent foramen ovale and stroke
Journal of Neurology, 2018A patent foramen ovale (PFO) is a highly prevalent finding in cryptogenic ischaemic stroke, particularly in young adults. A common challenge in clinical practice is to distinguish between incidental and pathogenic PFO. Some clinical features and tools such as the Risk of Paradoxical Embolism score may help determining the probability of a stroke ...
Miranda, Bruno +2 more
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Patent Foramen Ovale and Migraine
The American Journal of Cardiology, 2006AbstractMigraine is a common neurological disorder with a great impact on the quality of life and social activities. The patent foramen ovale (PFO) is an intra‐atrial right‐to‐left shunt with a prevalence of 25% in the general population. An increased prevalence is found in patients with migraine, especially in migraine with aura.
Martijn C. Post +3 more
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Heart, 1999
A 61 year old man presented with a cryptogenic cerebrovascular insult. Transoesophageal echocardiography (A) showed a patent foramen ovale (thin arrow). Agitated Haemaccel …
Beat C. Aeschbacher +2 more
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A 61 year old man presented with a cryptogenic cerebrovascular insult. Transoesophageal echocardiography (A) showed a patent foramen ovale (thin arrow). Agitated Haemaccel …
Beat C. Aeschbacher +2 more
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Patent Foramen Ovale and Stroke
Mayo Clinic Proceedings, 2004A patent foramen ovale (PFO) is a frequent remnant of embryological development with clinical importance in thromboembolism, paradoxical embolism, stroke, platypnea-orthodeoxia, decompression sickness, and migraine headache. The proposed mechanisms of stroke with PFO include paradoxical embolization, in situ thrombosis within the canal of the PFO ...
T. Jared Bunch, Steven C. Horton
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Migraine and Patent Foramen Ovale [PDF]
Current Neurology and Neuroscience Reports, 2014 Migraine is a widespread disorder with a large impact on society. Patent foramen ovale (PFO) is a common occurrence, affecting about 25 % of the population. Observational studies report PFO to be more prevalent in patients with migraine with aura, and patients with migraine with aura have a higher incidence of PFO.
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Patent Foramen Ovale Not So Patent
Echocardiography, 2009Transesophageal echocardiography (TEE) with agitated saline contrast is the most sensitive tool for diagnosing patent foramen ovale (PFO), but false positives can result. We report a patient who underwent a TEE during the study of a cryptogenic stroke. Contrast appeared in the left atrium with the Valsalva maneuver. However, the contrast exit site was
Francisco López-Pardo +3 more
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