Results 61 to 70 of about 28,790 (211)

Increased prevalence of potential right-to-left shunting in children with sickle cell anaemia and stroke [PDF]

, 2017
'Paradoxical' embolization via intracardiac or intrapulmonary right-to-left shunts (RLS) is an established cause of stroke. Hypercoagulable states and increased right heart pressure, which both occur in sickle cell anaemia (SCA), predispose to ...
Dlamini, N, Dowling, MM, Hynan, LS, Inusa, B, Iyer, R, Johnson, C, Kanter, J, Kirkham, F, Kwiatkowski, JL, Neumayr, L, Osunkwo, I, Owen, W, Panepinto, JA, PFAST Investigators, ., Plumb, PA, Quinn, CT, Ramaciotti, C, Rhodes, M, Sarnaik, S, Strouse, JJ   +19 more
core   +1 more source

Repurposing With Purpose: Treatment of Bachmann–Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Rare diseases impact approximately 1 in 10 people worldwide, and yet, less than 5% of all rare diseases currently have an approved treatment option available. This is due to many challenges unique to rare diseases, including small, diverse patient populations, the cost of drug development that is not proportionate to the number of patients who
Caleb P. Bupp, Elizabeth A. VanSickle, Julianne Michael, Chad R. Schultz, Kelly Nguyen, Melissa Hoefer, Surender Rajasekaran, André S. Bachmann   +7 more
wiley   +1 more source

Paradoxical Embolism due to Persistent Foramen Ovale; a Case Report

Archives of Academic Emergency Medicine, 2016
The mean percentage of cryptogenic strokes among ischemic strokes is 31%, of which one-third may be associated with patent foramen ovale. The foramen ovale is required for blood flow through the fetal atrial septum.  It is formed as of the fourth week ...
Dormar David Barrios, Jonathan Roncancio, Albert Alejandro Avila, Jaime Andrés Alvarado, Ana Cristina Montenegro   +4 more
doaj   +3 more sources

Local DRLs and automated risk estimation in paediatric interventional cardiology [PDF]

, 2019
Introduction : Cardiac catheterization procedures result in high radiation doses and often multiple procedures are necessary for congenital heart disease patients. However, diagnostic reference levels (DRL) remain scarce.
Bacher, Klaus, Buytaert, Dimitri, De Wolf, Daniël, PANZER, JOSEPH, Rubbens, Lukas, Vandekerckhove, Kristof   +5 more
core   +2 more sources

Management of Cardiovascular Health Issues in Turner Syndrome: Expert Insights and Expanded Recommendations From the 2024 Guideline Development Team

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote, Sheetal R. Patel, Kristian Havmand Mortensen, Isabel Witvrouwen, Anthonie Duijnhouwer, Nicole M. Brown, Jasmine Grewal, Kathryn C. Chatfield, Aaron T. Dorfman, Siddharth K. Prakash   +9 more
wiley   +1 more source

“Visiting scientist effect”? Exploring the impact of time‐lags in the digitization of 2D landmark data

The Anatomical Record, EarlyView.
Abstract Measurement error (ME) in geometric morphometrics has been the subject of countless articles, but none specific to the effect of time lags on landmark digitization error. Yet, especially for visiting scientists working on museum collections, it is not uncommon to collect data in multiple rounds, with interruptions of weeks or years. To explore
Andrea Cardini
wiley   +1 more source

Active paradoxical and pulmonary emboli in a first trimester pregnancy

Annals of Cardiac Anaesthesia, 2022
Capturing a paradoxical embolism in real-time has been a challenge in recent literature. We present the unique case of a 33-year-old, G3P2 female at 8 weeks gestation presenting with dyspnea. An active thrombus through an undiagnosed patent foramen ovale
Nicholas Suraci, Monica Shifman, Annadita Kumar, Michael Haske   +3 more
doaj   +1 more source

Exploring the relationship between entertainment and education in anatomy public engagement: A qualitative examination of anatomists' perspectives

Anatomical Sciences Education, EarlyView.
Abstract Entertainment is deeply rooted in education, from wise‐cracking teachers to health documentaries. In the context of anatomy, this already complex relationship is entwined with deeply significant ethical considerations, often related to the field's reliance on human tissue, yet it remains unexplored.
Lucas D. Wilmshurst, Lauren Clunie, Kieron Brand, Chandini Parsan Chand, Kat A. Sanders   +4 more
wiley   +1 more source

Patent foramen ovale and migraine in ischemic stroke patients: incidence, pathogenetic interrelation and the effects of endovascular closure [PDF]

Клиническая практика
BACKGROUND: Migraine is a chronic neurovascular disease with high incidence rate and medical-social significance. Despite more than half a century of studying the disease, the pathogenesis of migraine is not yet completely clear.
Anastasia V. Belopasova, Andrey O. Chechetkin, Viktor D. Merezhko   +2 more
doaj   +1 more source

Secondary stroke prevention: patent foramen ovale, aortic plaque, and carotid stenosis [PDF]

, 2017
Stroke is the most debilitating cardiovascular event. It has a variety of causes that may be present simultaneously. In young or otherwise healthy people, the search for a patent foramen ovale (PFO) has become standard.
Diener, Hans C., Frank, Benedikt, Meier, Bernhard, Wahl, Andreas   +3 more
core