Results 61 to 70 of about 28,297 (220)

Repurposing With Purpose: Treatment of Bachmann–Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Rare diseases impact approximately 1 in 10 people worldwide, and yet, less than 5% of all rare diseases currently have an approved treatment option available. This is due to many challenges unique to rare diseases, including small, diverse patient populations, the cost of drug development that is not proportionate to the number of patients who
Caleb P. Bupp   +7 more
wiley   +1 more source

Percutaneous Closure of Patent Foramen Ovale in a Patient with Mirror-Image Dextrocardia and Situs Inversus

open access: yesCardiovascular Innovations and Applications, 2020
A 26-year-old patient with mirror-image dextrocardia and situs inversus experienced a transient ischemic attack. We suspected that a patent foramen ovale was the reason.
Xiaofei Jiang, Heng Zhang, Mingyang Qian
doaj   +1 more source

Management of Cardiovascular Health Issues in Turner Syndrome: Expert Insights and Expanded Recommendations From the 2024 Guideline Development Team

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote   +9 more
wiley   +1 more source

Paradoxical Embolism due to Persistent Foramen Ovale; a Case Report

open access: yesArchives of Academic Emergency Medicine, 2016
The mean percentage of cryptogenic strokes among ischemic strokes is 31%, of which one-third may be associated with patent foramen ovale. The foramen ovale is required for blood flow through the fetal atrial septum.  It is formed as of the fourth week ...
Dormar David Barrios   +4 more
doaj   +3 more sources

“Visiting scientist effect”? Exploring the impact of time‐lags in the digitization of 2D landmark data

open access: yesThe Anatomical Record, EarlyView.
Abstract Measurement error (ME) in geometric morphometrics has been the subject of countless articles, but none specific to the effect of time lags on landmark digitization error. Yet, especially for visiting scientists working on museum collections, it is not uncommon to collect data in multiple rounds, with interruptions of weeks or years. To explore
Andrea Cardini
wiley   +1 more source

Exploring the relationship between entertainment and education in anatomy public engagement: A qualitative examination of anatomists' perspectives

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Entertainment is deeply rooted in education, from wise‐cracking teachers to health documentaries. In the context of anatomy, this already complex relationship is entwined with deeply significant ethical considerations, often related to the field's reliance on human tissue, yet it remains unexplored.
Lucas D. Wilmshurst   +4 more
wiley   +1 more source

Active paradoxical and pulmonary emboli in a first trimester pregnancy

open access: yesAnnals of Cardiac Anaesthesia, 2022
Capturing a paradoxical embolism in real-time has been a challenge in recent literature. We present the unique case of a 33-year-old, G3P2 female at 8 weeks gestation presenting with dyspnea. An active thrombus through an undiagnosed patent foramen ovale
Nicholas Suraci   +3 more
doaj   +1 more source

Secondary stroke prevention: patent foramen ovale, aortic plaque, and carotid stenosis [PDF]

open access: yes, 2017
Stroke is the most debilitating cardiovascular event. It has a variety of causes that may be present simultaneously. In young or otherwise healthy people, the search for a patent foramen ovale (PFO) has become standard.
Diener, Hans C.   +3 more
core  

Atrial Septal Defects [PDF]

open access: yes, 2014
Atrial septal defects are the third most common type of congenital heart disease. Included in this group of malformations are several types of atrial communications that allow shunting of blood between the systemic and the pulmonary circulations.
Geva, T, Martins, JD, Wald, R
core   +1 more source

Site‐Specific Antithrombotic Therapy: 24‐Month Outcomes of the Randomized DESyne BDS Plus Trial Using a Novel Triple‐Drug Eluting Coronary Implant With Two Anticoagulants and Sirolimus

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background DESyne BDS Plus represents a novel triple drug therapy (TRx) applied on a coronary stent platform eluting the antiproliferative drug Sirolimus along with two anticoagulants (Rivaroxaban and Argatroban) to reduce the site‐specific thrombotic risk.
Stefan Verheye   +19 more
wiley   +1 more source

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