Results 61 to 70 of about 17,584 (185)
Background: Stroke is the third cause of mortality and leading cause of disability regarding the World Health Organization data. Cryptogenic stroke encompasses 40% of young adults with ischemic stroke.
Marjan Zaletel +3 more
doaj
Abstract Introduction Pregnant people with congenital heart disease (CHD) are a growing patient population in obstetrics, yet evidence on the risk for severe maternal morbidity (SMM) has largely been limited to studies that lack specificity for CHD. We conducted this study to demonstrate the utility of distributed data networks for obstetric research ...
Elizabeth B. Sherwin +11 more
wiley +1 more source
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
ABSTRACT Noonan syndrome (NS) is a genetically heterogeneous disorder characterized by a broad spectrum of clinical features resulting from dysregulation of the RAS/MAPK pathway. Although complex genotypes are increasingly recognized in NS, cases harboring two distinct pathogenic variants in different NS genes remain extremely rare.
Francesco Prevedello +10 more
wiley +1 more source
Phenotype Expansion of Malan Syndrome: New Cases and a Review of the Literature
ABSTRACT Malan syndrome is an ultra‐rare overgrowth syndrome caused by pathogenic variants or deletions in nuclear factor one X (NFIX) located at 19p13.2. Here, we report a comprehensive literature review and phenotyping of known patients with Malan syndrome and present a novel cohort of eight patients.
Alex F. Nisbet +10 more
wiley +1 more source
Cryptogenic stroke and patent foramen ovale (abridged and translated version)
Interventional patent foramen ovale (PFO) closure should be performed in patients aged 16 to 60 years (after extensive neurological and cardiological diagnostic work-up) with a history of cryptogenic ischaemic stroke and patent foramen ovale, with ...
Hans-Christoph Diener +2 more
doaj +1 more source
PATENT FORAMEN OVALE AND DIVING
Although patent foramen ovale (PFO) was anatomically depicted in 1513 by Leonardo da Vinci and described as a thromboembolism route in 1877, it has been ignored for a long time as a potential way to produce pathological conditions. The unifying hypothesis associated with multiple clinical issues, such as cryptogenic stroke, migraine and decompression ...
openaire +3 more sources
ABSTRACT Background Hybrid stage I palliation (HS1P) has developed as an alternative to the Norwood stage I palliation for neonates with hypoplastic left heart and related left‐sided obstructive lesions. HS1P is currently used in various clinical settings, such as single ventricle palliation, bridge to decision, bridge to biventricular repair, or ...
Johanna Hummel +8 more
wiley +1 more source
Combined cardiac and abdominal surgery in a child with nephroblastoma, inferior vena cava tumor thrombus extending to the right atrium, and patent foramen ovale. ABSTRACT Wilms tumor with intravascular extension poses significant surgical challenges, particularly when combined with a patent foramen ovale, which adds the risk of paradoxical embolism. We
Lea‐Kathrin Hammer +8 more
wiley +1 more source
Finite Element Simulation Analysis of a Nickel-Titanium Alloy Patent Foramen Ovale Occluder
In this paper, a preliminary stress/strain analysis of the design structure of a nickel-titanium alloy patent foramen ovale occluder is conducted with the finite element simulation analysis method. In the analysis, solid structure modeling is carried out
Juan SHEN, Wei LIU
doaj +1 more source

