Results 91 to 100 of about 291,405 (288)

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Granular Impact: A Grain-scale Approach

, 2015
This work summarizes a series of studies on two-dimensional granular impact, where an intruding object strikes a granular material at high speed. Many previous studies on granular impact have used a macroscopic force law, which is dominated by an ...
Allen, Ambroso, Atman, Bassett, Baxter, Bi, Brendel, Clark, Clark, Clark, Cundall, Da Silva, Daniels, Dantu, de Bruyn, Drescher, Drescher, Forrestal, Geng, Geng, Geng, Goldenberg, Goldman, Gómez, Howell, Kondic, Kondic, Krim, Liu, Majmudar, Majmudar, Nelson, Nesterenko, Nesterenko, Newhall, Pica Ciamarra, Poncelet, Puckett, Radjai, Ren, Schäfer, Seguin, Takehara, Tordesillas, Tsimring, Umbanhowar, Utter, Wakabayashi, Walsh, Zhang   +49 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Error estimation of the physical and mechanical characteristics measurements by indentation

Приборы и методы измерений, 2018
The active application in the practice of testing the indentation methods, in particular to measure the physical and mechanical properties of metals, polymers, biological technologies demands to development techniques for the measurement error estimation.
A. P. Kren, O. V. Matsulevich, M. N. Delendik   +2 more
doaj   +1 more source

Texture evolution of "Amaretti" cookies during storage [PDF]

, 2006
The results of a study on texture evolution during 35 days of storage of ldquoamarettirdquo, a typical Italian cookie, packaged in two different ways are reported.
Catzeddu, Pasquale, Piga, Antonio <1965- >, Roggio, Tonina, Scano, Efisio Antonio   +3 more
core  

Surface patterning of carbon nanotubes can enhance their penetration through a phospholipid bilayer

, 2012
Nanotube patterning may occur naturally upon the spontaneous self-assembly of biomolecules onto the surface of single-walled carbon nanotubes (SWNTs). It results in periodically alternating bands of surface properties, ranging from relatively hydrophilic
Balasubramanian K., Campbell J. F., Chattopadhyay J., Cheng C., Dalton A. B., Davoren M., Dieckmann G. R., Gigliotti B., Ju S.-Y., Kam N. W. S., Kam N. W. S., Klumpp C., Kouklin N. A., Liu J., Liu Q., Nigel K. H. Slater, Numata M., Pantarotto D., Pantarotto D., Pogodin S., Pogodin S., Porter A. E., Porter A. E., Richard C., Sergey Pogodin, Smart S., Thauvin C., Tu X., Verma A., Vernizzi G., Vladimir A. Baulin, Yang K., Zhang X., Zorbas V.   +33 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source