Results 41 to 50 of about 33,310 (219)

Analysis on the crimping quality of overhead transmission line conductors considering equivalent cross-sectional stiffness

open access: yesAIP Advances, 2022
Approximately 58% of wire failures are caused by slippage and fracture of electrical connectors, and the crimping quality analysis of connectors is based on equivalent cross-sectional stiffness.
Wei Zhang   +3 more
doaj   +1 more source

Study on softening characteristics of mudstones in shallow buried strata in Xinjiang and countermeasures for tunnel support

open access: yes矿业科学学报, 2021
The Xinjiang water conveyance tunnel is a shallow buried mudstone stratum. After the water absorption, the strength of the surrounding rock softens and large deformation occurs.
Zhang Yong   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Innovative Design and Performance Evaluation of Bionic Imprinting Toothed Wheel

open access: yesApplied Bionics and Biomechanics, 2018
A highly efficient soil-burrowing dung beetle possesses an intricate outer contour curve on its foreleg end-tooth. This study was carried out based on evidence that this special outer contour curve has the potential of reducing soil penetration ...
Zhihong Zhang   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Finite element simulation of the complete sheet metal blanking cycle: Effect of blanking clearance on force curve and cut edge quality

open access: yesHeliyon
Sheet metal blanking process is a manufacturing process that is widely used in sheet metal forming and particularly in the electronics and automotive industries.
Jean Rizk   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

NEW MECHANISMS FOR NANOINDENTATION DATA PROCESSING USING ATOMIC FORCE MICROSCOPY METHOD

open access: yesНаука и техника, 2015
Elastic modulus accuracy using atomic force microscopy  depends significantly on processing quality of the experimental data obtained during nanoindentation.  Multiply repeated calibration can lead to conservative value of the calibration factor.
A. A. Mohammed Salem   +3 more
doaj  

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