Results 91 to 100 of about 3,209,374 (307)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Heat Equation to 3D Image Segmentation [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2006
This paper presents a new approach, capable of 3D image segmentation and objects' surface reconstruction. The main advantages of the method are: large capture range; quick segmentation of a 3D scene/image to regions; multiple 3D objects reconstruction ...
Nikolay Sirakov
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Evaluating Stacked Dielectric Elastomer Actuators as Soft Motor Units for Forming Artificial Muscles in Biomimetic Rehabilitation Robots

open access: yesActuators
The recent commercial availability of stacked dielectric elastomer actuators (SDEAs) has unlocked new opportunities for their application as “artificial skeletal muscles” in rehabilitation robots and powered exoskeletons.
Vahid Mohammadi   +4 more
doaj   +1 more source

On the decomposition of forces

open access: yesTheoretical and Applied Mechanics Letters, 2014
We show that any continuously differentiable force is decomposed into the sum of a Rayleigh force and a gyroscopic force. We also extend this result to piecewise continuously differentiable forces. Our result improves the result on the decomposition of forces in a book by David Merkin and further extends it to piecewise continuously differentiable ...
openaire   +3 more sources

On the Terms “Centrifugal Force” and “Force of Inertia” [PDF]

open access: yesNature, 1892
THE retention, in the last edition of Mr. Loney's “Elements of Dynamics,” 1891, of a paragraph (p. 141) which resuscitates the objections formerly urged by some writers against the use of the term “centrifugal force” seems to call for a protest. It is to be regretted that students of dynamics should find absolutely contradictory statements presented to
openaire   +2 more sources

Ninth Flyer 17_3_2007

open access: yes, 2014
The quarterly newsletter, The Ninth Flyer, published by the Ninth Air Force Association, Inc.
9th Air Force Association
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Starters vs. non-starters differences in vertical jump force-time metrics in female professional volleyball players

open access: yesFrontiers in Sports and Active Living
As one of the fundamental volleyball skills, countermovement vertical jump (CMJ) has been commonly implemented in the applied sports setting as a non-invasive and time-efficient assessment of athletes' lower-body neuromuscular function.
Damjana V. Cabarkapa   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy