Results 91 to 100 of about 3,209,374 (307)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Heat Equation to 3D Image Segmentation [PDF]
This paper presents a new approach, capable of 3D image segmentation and objects' surface reconstruction. The main advantages of the method are: large capture range; quick segmentation of a 3D scene/image to regions; multiple 3D objects reconstruction ...
Nikolay Sirakov
doaj
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The recent commercial availability of stacked dielectric elastomer actuators (SDEAs) has unlocked new opportunities for their application as “artificial skeletal muscles” in rehabilitation robots and powered exoskeletons.
Vahid Mohammadi +4 more
doaj +1 more source
On the decomposition of forces
We show that any continuously differentiable force is decomposed into the sum of a Rayleigh force and a gyroscopic force. We also extend this result to piecewise continuously differentiable forces. Our result improves the result on the decomposition of forces in a book by David Merkin and further extends it to piecewise continuously differentiable ...
openaire +3 more sources
On the Terms “Centrifugal Force” and “Force of Inertia” [PDF]
THE retention, in the last edition of Mr. Loney's “Elements of Dynamics,” 1891, of a paragraph (p. 141) which resuscitates the objections formerly urged by some writers against the use of the term “centrifugal force” seems to call for a protest. It is to be regretted that students of dynamics should find absolutely contradictory statements presented to
openaire +2 more sources
The quarterly newsletter, The Ninth Flyer, published by the Ninth Air Force Association, Inc.
9th Air Force Association
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
As one of the fundamental volleyball skills, countermovement vertical jump (CMJ) has been commonly implemented in the applied sports setting as a non-invasive and time-efficient assessment of athletes' lower-body neuromuscular function.
Damjana V. Cabarkapa +2 more
doaj +1 more source

