Results 41 to 50 of about 2,637,757 (313)

A Biomechanical Analysis of Wide, Medium, and Narrow Grip Width Effects on Kinematics, Horizontal Kinetics, and Muscle Activity on the Sticking Region in Recreationally Trained Males During 1-RM Bench Pressing

open access: yesFrontiers in Sports and Active Living, 2021
Grip width has been found to affect lifting performance, especially around the sticking region; however, little is known about the kinetics and muscle activities that could explain these differences in performance.
Stian Larsen   +2 more
doaj   +1 more source

Forcing brushes

open access: yesDiscrete Applied Mathematics, 2019
We give short and simple proofs of the inequalities $B(G)\leq Z(L(G))$ and $Z(G)\leq Z(L(G))$ first established by Erzurumluoğlu, Meagher, and Pike, where $G$ is a graph without isolated vertices, $B(G)$ is the brushing number of $G$, $Z(G)$ is the zero forcing number of $G$, and $L(G)$ is the line graph of $G$.
Dirk Meierling, Dieter Rautenbach
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Pareto on Cunning and Deceit

open access: yesHistories
In Plato’s Republic, Socrates praises reason and vilifies force. This preference for reason continued its role in philosophy and only a few political thinkers considered the use of force. Plato also dismissed persuasion as the Sophists’ art of making the
Christopher Adair-Toteff
doaj   +1 more source

Force-Induced Changes of PilY1 Drive Surface Sensing by Pseudomonas aeruginosa

open access: yesmBio, 2022
During biofilm formation, the opportunistic pathogen Pseudomonas aeruginosa uses its type IV pili (TFP) to sense a surface, eliciting increased second-messenger production and regulating target pathways required to adapt to a surface lifestyle.
Shanice S. Webster   +9 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

First-line treatment of metastatic melanoma: role of nivolumab

open access: yesImmunoTargets and Therapy, 2017
Jeremy Force,1 April KS Salama,1,2 1Division of Hematology/Oncology, Duke University Medical Center, Durham, NC, USA; 2Division of Medical Oncology, Duke University Medical Center, Durham, NC, USA Abstract: Historically, the median overall survival of ...
Force J, Salama AK
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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