Results 121 to 130 of about 1,077,204 (312)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Characterization of superspreaders movement in a bidirectional corridor using a social force model. [PDF]

Front Public Health, 2023
Kanté DSI, Jebrane A, Hakim A, Boukamel A.   +3 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Force and Trajectory Control of Industrial Robots in Stiff Contact

, 2013
Position-based force control is presented, incorporating compliance in the robot joints and possibly in a force- / torque-sensor and/or the environment. First, the total compliance is identified.
Michael Suppa, Suppa, Michael, Friedrich Lange, Wieland Bertleff, Bertleff, Wieland, Lange, Friedrich   +5 more
core   +1 more source

Experimental Investigation of Subcutaneous Pressure and Shear Force Changes Using a Bone Protrusion Model as a Risk Factor for Pressure Ulcer Development

Journal of Plastic and Reconstructive Surgery, 2023
Objectives: Subcutaneous pressure and subcutaneous shear force were investigated using a bone protrusion model to investigate a polyurethane film dressing (hereinafter referred to as adhesive film) for preventing shear force. Our hypothesis was that when
Munetomo Nagao, Takehiko Ohura, Makoto Takahashi, Masayuki Osawa   +3 more
doaj  

Influence of two kinds of clearance joints on the dynamics of planar mechanical system based on a modified contact force model. [PDF]

Sci Rep, 2023
Tan H, Li L, Huang Q, Jiang Z, Li Q, Zhang Y, Yu D.   +6 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

The win-first probability under interest force [PDF]

In a classical risk model under constant interest force, we study the probability that the surplus of an insurance company reaches an upper barrier before a lower barrier. We define this probability as win-first probability.
Stéphane Loisel, Didier Rullière
core  

Optomechanical damping of a microcantilever force sensor in liquid [PDF]

, 2010
A new instrument, constant deflection atomic force microscopy (CD-AFM) constructed to perform force spectroscopy measurements without mechanical instabilities associated with the use of soft AFM cantilevers has been developed, tested and calibrated ...
Al Zahrani, Khalid Eidah
core