Results 151 to 160 of about 529,798 (193)
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Molecular Force Spectroscopy on Cells
Annual Review of Physical Chemistry, 2015Molecular force spectroscopy has become a powerful tool to study how mechanics regulates biology, especially the mechanical regulation of molecular interactions and its impact on cellular functions. This force-driven methodology has uncovered a wealth of new information of the physical chemistry of molecular bonds for various biological systems.
Baoyu, Liu, Wei, Chen, Cheng, Zhu
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1996
Two-dimensional histogram technique is used to determine the loading dependence of friction. Multifunctional dependence F F i (F N )is observed, where the index i represents different materials or inequivalent sites. The data are found to be in agreement with simple power laws, corresponding to the single asperity regime with contact radii of 1–4nm (1 ...
E. Meyer +9 more
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Two-dimensional histogram technique is used to determine the loading dependence of friction. Multifunctional dependence F F i (F N )is observed, where the index i represents different materials or inequivalent sites. The data are found to be in agreement with simple power laws, corresponding to the single asperity regime with contact radii of 1–4nm (1 ...
E. Meyer +9 more
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Small Amplitude Atomic Force Spectroscopy
2010Over the years atomic force microscopy has developed from a pure imaging technique to a tool that can be employed for measuring quantitative tip–sample interaction forces. In this chapter we provide an overview of various techniques to extract quantitative tip–sample forces focusing on both amplitude modulation and frequency modulation atomic force ...
de Beer, Sissi +3 more
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2007
Weak-noncovalent interactions govern structural cohesion and mediate most of life’s functions from the outer membrane surface to the interior nucleus of a cell. On laboratory time scales, the energy landscape of a weak bond is fully explored by Brownian-thermal excitations, and energy barriers along its dissociation pathway(s) become encoded in a rate ...
E. Evans, P. Williams
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Weak-noncovalent interactions govern structural cohesion and mediate most of life’s functions from the outer membrane surface to the interior nucleus of a cell. On laboratory time scales, the energy landscape of a weak bond is fully explored by Brownian-thermal excitations, and energy barriers along its dissociation pathway(s) become encoded in a rate ...
E. Evans, P. Williams
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Dielectrophoresis force spectroscopy for colloidal clusters
ELECTROPHORESIS, 2012Optical trapping‐based force spectroscopy was used to measure the frequency‐dependent DEP forces and DEP crossover frequencies of colloidal polymethyl methacrylate spheres and clusters. A single sphere or cluster, held by an optical tweezer, was positioned near the center of a pair of gold‐film electrodes where alternating current elecroosmosis flow ...
Park, H Park, Hyunjoo +2 more
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Correlation Force Spectroscopy
2015The main advantage of correlation force spectroscopy (CFS) over atomic force microscopy (AFM) is that the thermal noise in the cross-correlation between two cantilevers (CFS design) is much smaller than the thermal noise in the autocorrelation of a single cantilever (AFM design). In this chapter, this is examined experimentally.
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Single Molecule Force Spectroscopy
2015Molecular-scale forces has a pivotal role in biological, chemical and physical processes. Single molecule force spectroscopy refers to the study of these forces as well as the mechanical properties of single molecules under applied forces. The term has appeared more than two decades ago in the field of biochemistry, however the recent advances of ...
Pawlak, Rémy +3 more
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Magnetic Exchange Force Spectroscopy
2015Magnetic exchange force spectroscopy is an elegant experimental method to extract the short-range magnetic contribution to the total interatomic interaction energy between the tip apex atom and the sample atoms across a vacuum gap. If the tip does not exhibit a spin-dependent reversible hysteretic reconfiguration of its atomic structure, experimental ...
Alexander Schwarz, Stefan Heinze
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Simulation in Force Spectroscopy
2008Simulation has played an important role in the study of molecular-scale forces since the 1970s, almost from the time such forces could first be measured experimentally. Over the past three decades, as experimental probes have grown in sophistication and sensitivity, the scope and accuracy of computer modeling have developed in step.
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