Results 11 to 20 of about 156,558 (310)

Single-cell force spectroscopy [PDF]

Journal of Cell Science, 2008
The controlled adhesion of cells to each other and to the extracellular matrix is crucial for tissue development and maintenance. Numerous assays have been developed to quantify cell adhesion. Among these, the use of atomic force microscopy (AFM) for single-cell force spectroscopy (SCFS) has recently been established. This assay permits the adhesion of
Helenius, J., Heisenberg, C., Gaub, H., Müller, D.   +3 more
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Concurrent Atomic Force Spectroscopy [PDF]

Communications Physics, 2018
ABSTRACTForce-spectroscopy by Atomic Force Microscopy (AFM) is the technique of choice to measure mechanical properties of molecules, cells, tissues and materials at the nano and micro scales. However, unavoidable calibration errors of AFM probes make it cumbersome to quantify modulation of mechanics.
Carolina Pimenta-Lopes, Carmen Suay-Corredera, Diana Velázquez-Carreras, David Sánchez-Ortiz, Jorge Alegre-Cebollada   +4 more
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Quark Forces from Hadronic Spectroscopy [PDF]

Physical Review Letters, 2009
We consider the implications of the most general two-body quark-quark interaction Hamiltonian for the spin-flavor structure of the negative parity L=1 excited baryons. Assuming the most general two-body quark interaction Hamiltonian, we derive two correlations among the masses and mixing angles of these states, which constrain the mixing angles, and ...
Pirjol, Dan, Schat, Carlos Luis
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Assessment of Efficacy of a Novel Crosslinking Protocol with Intracameral Oxygen (Bubble-CXL) in Increasing the Corneal Stiffness Using Atomic Force Microscopy

Nanomaterials, 2022
The environmental oxygen level plays a critical role in corneal crosslinking (CXL), a treatment method to increase corneal biomechanical stability. In this study, we introduce a new CXL method (Bubble-CXL), in which intracameral oxygen serves as an ...
Ammar Alkhalde, Hannah Seferovic, Ali Abri, Alvana Simbrunner, Peter Hinterdorfer, Yoo Jin Oh   +5 more
doaj   +1 more source

3D Force Field Spectroscopy [PDF]

, 2015
With recent advances in instrumentation and experimental methodology, noncontact atomic force microscopy is now being frequently used to measure the atomic-scale interactions acting between a sharp probe tip and surfaces of interest as a function of three spatial dimensions, via the method of three-dimensional atomic force microscopy (3D-AFM).
Baykara, M.Z., Schwarz, U.D.
openaire   +4 more sources

Force Spectroscopy with Quantitative On-Cantilever Force Control

Proceedings, 2018
In this work we propose a method for on-cantilever force control for application in force distance (F-z) spectroscopy for intermolecular interaction sensing.
Wojciech Majstrzyk, Karolina Orlowska, Andrzej Sierakowski, Rafał Dobrowolski, Teodor Gotszalk   +4 more
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Using Single-Molecule Chemo-Mechanical Unfolding to Simultaneously Probe Multiple Structural Parameters in Protein Folding

Methods and Protocols, 2019
While single-molecule force spectroscopy has greatly advanced the study of protein folding, there are limitations to what can be learned from studying the effect of force alone.
Emily J. Guinn, Susan Marqusee
doaj   +1 more source

Pathogen-host adhesion between SARS-CoV-2 spike proteins from different variants and human ACE2 studied at single-molecule and single-cell levels

Emerging Microbes and Infections, 2022
The binding of the receptor binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein onto human angiotensin-converting enzyme 2 (ACE2) is considered as the first step for the virus to adhere onto the host cells ...
Xiaoxu Zhang, Bixia Hong, Peng Wei, Pengfei Pei, Haifeng Xu, Long Chen, Yigang Tong, Jialin Chen, Shi-Zhong Luo, Huahao Fan, Chengzhi He   +10 more
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Altered Envelope Structure and Nanomechanical Properties of a C-Terminal Protease A-Deficient Rhizobium leguminosarum

Microorganisms, 2020
(1) Background: Many factors can impact bacterial mechanical properties, which play an important role in survival and adaptation. This study characterizes the ultrastructural phenotype, elastic and viscoelastic properties of Rhizobium leguminosarum bv ...
Dong Jun, Ubong Idem, Tanya E. S. Dahms
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A new method for obtaining model-free viscoelastic material properties from atomic force microscopy experiments using discrete integral transform techniques

Beilstein Journal of Nanotechnology, 2021
Viscoelastic characterization of materials at the micro- and the nanoscale is commonly performed with the aid of force–distance relationships acquired using atomic force microscopy (AFM).
Berkin Uluutku, Enrique A. López-Guerra, Santiago D. Solares   +2 more
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