Results 31 to 40 of about 156,558 (310)
Background: Noncontact atomic force microscopy (NC-AFM) now regularly produces atomic-resolution images on a wide range of surfaces, and has demonstrated the capability for atomic manipulation solely using chemical forces.
Adam Sweetman +3 more
doaj +1 more source
Measurements of the frequency shift versus distance in noncontact atomic force microscopy (NC-AFM) allow measurements of the force gradient between the oscillating tip and a surface (force-spectroscopy measurements).
Manfred Lange +2 more
doaj +1 more source
OPTICAL PROPERTIES OF CdS–Ag2S QUANTUM DOT SYSTEM
The paper presents the results of a study of systems with quantum dots of two types: CdS and Ag2S, which have different types of crystal lattices. CdS quantum dots were synthesized in the gelatin matrix by means of the sol-gel method.
Bezdetko Yulia S. +2 more
doaj +1 more source
AFM Probing of Amyloid-Beta 42 Dimers and Trimers
Elucidating the molecular mechanisms in the development of such a devastating neurodegenerative disorder as Alzheimer’s disease (AD) is currently one of the major challenges of molecular medicine.
Sibaprasad Maity, Yuri L. Lyubchenko
doaj +1 more source
Atomic force microscopy-single-molecule force spectroscopy unveils GPCR cell surface architecture
Atomic force microscopy-based single molecule force spectroscopy reveals the unfolding of G-protein coupled receptors on the surface of living mammalian cells.
Etienne Dague +10 more
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Modification of a single-molecule AFM probe with highly defined surface functionality
Single-molecule force spectroscopy with an atomic force microscope has been widely used to study inter- and intramolecular interactions. To obtain data consistent with single molecular events, a well-defined method is critical to limit the number of ...
Fei Long +4 more
doaj +1 more source
The geometry of two-dimensional crystalline membranes is of interest given its unique synergistic interplay with their mechanical, chemical, and electronic properties. For one-atom-thick graphene, these properties can be substantially modified by bending
Makoto Ashino, Roland Wiesendanger
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Twisting and extension: Application of magnetic tweezers to DNA studies
Magnetic tweezers have emerged as a vital force spectroscopy tool for characterizing the mechanical properties of nucleic acids and their interactions with proteins.
Arsha Moorthy +3 more
doaj +1 more source

