Results 51 to 60 of about 529,798 (193)

Protein unfolding and refolding as transitions through virtual states [PDF]

open access: yes, 2014
Single-molecule atomic force spectroscopy probes elastic properties of titin, ubiquitin and other relevant proteins. We explain bioprotein folding dynamics under both length- and force-clamp by modeling polyprotein modules as particles in a bistable ...
Bonilla, L. L., Carpio, A., Prados, A.
core   +3 more sources

pH-Dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy

open access: yesMolecules, 2014
Avidin and avidin-like proteins are widely used in numerous techniques since the avidin-biotin interaction is known to be very robust and reliable. Within this study, we investigated this bond at the molecular level under harsh conditions ranging from ...
Melanie Köhler   +6 more
doaj   +1 more source

Optimization of Protein-Protein Interaction Measurements for Drug Discovery Using AFM Force Spectroscopy [PDF]

open access: yes, 2019
Increasingly targeted in drug discovery, protein-protein interactions challenge current high throughput screening technologies in the pharmaceutical industry.
Basson, Marc D.   +11 more
core   +1 more source

Measurement of electron-hole friction in an n-doped GaAs/AlGaAs quantum well using optical transient grating spectroscopy [PDF]

open access: yes, 2011
We use phase-resolved transient grating spectroscopy to measure the drift and diffusion of electron-hole density waves in a semiconductor quantum well.
D. R. Tibbetts   +9 more
core   +1 more source

OPTICAL PROPERTIES OF CdS QUANTUM DOTS SYNTHESIZED AT DIFFERENT CONCENTRATIONS OF REAGENTS

open access: yesКонденсированные среды и межфазные границы, 2018
. The paper presents the results of the investigation of quantum dots of cadmium sulfi de synthesized by sol-gel technology in a gelatin matrix. Samples were obtained with different contents of the initial reagents. The concentrations were varied from 2·
Victor G. Klyuev   +2 more
doaj   +1 more source

West Nile Virus Capsid Protein Interacts With Biologically Relevant Host Lipid Systems

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
West Nile and dengue viruses are closely related flaviviruses, originating mosquito-borne viral infections for which there are no effective and specific treatments.
Ana S. Martins   +4 more
doaj   +1 more source

Spectroscopy of quadrupole and octupole states in rare-earth nuclei from a Gogny force [PDF]

open access: yes, 2015
Collective quadrupole and octupole states are described in a series of Sm and Gd isotopes within the framework of the interacting boson model (IBM), whose Hamiltonian parameters are deduced from mean field calculations with the Gogny energy density ...
Nomura, K.   +2 more
core   +4 more sources

High‐speed atomic force microscopy: Imaging and force spectroscopy

open access: yesFEBS Letters, 2014
Atomic force microscopy (AFM) is the type of scanning probe microscopy that is probably best adapted for imaging biological samples in physiological conditions with submolecular lateral and vertical resolution. In addition, AFM is a method of choice to study the mechanical unfolding of proteins or for cellular force spectroscopy.
Eghiaian, Frédéric   +4 more
openaire   +3 more sources

A guide to magnetic tweezers and their applications

open access: yesFrontiers in Physics, 2016
Magnetic force spectroscopy is a rapidly developing single molecule technique that found numerous applications at the interface of physics and biology. Since the invention of the first magnetic tweezers, a number of modifications were incorporated into ...
Rupa Sarkar, Valentin V Rybenkov
doaj   +1 more source

Probing Ligand-Receptor Interaction in Living Cells Using Force Measurements With Optical Tweezers

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
This work probes the binding kinetics of COOH-terminus of Clostridium perfringens enterotoxin (c-CPE) and claudin expressing MCF-7 cells using force spectroscopy with optical tweezers.
Carolin Riesenberg   +10 more
doaj   +1 more source

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