Protein unfolding and refolding as transitions through virtual states [PDF]
Single-molecule atomic force spectroscopy probes elastic properties of titin, ubiquitin and other relevant proteins. We explain bioprotein folding dynamics under both length- and force-clamp by modeling polyprotein modules as particles in a bistable ...
Bonilla, L. L., Carpio, A., Prados, A.
core +3 more sources
Avidin and avidin-like proteins are widely used in numerous techniques since the avidin-biotin interaction is known to be very robust and reliable. Within this study, we investigated this bond at the molecular level under harsh conditions ranging from ...
Melanie Köhler +6 more
doaj +1 more source
Optimization of Protein-Protein Interaction Measurements for Drug Discovery Using AFM Force Spectroscopy [PDF]
Increasingly targeted in drug discovery, protein-protein interactions challenge current high throughput screening technologies in the pharmaceutical industry.
Basson, Marc D. +11 more
core +1 more source
Measurement of electron-hole friction in an n-doped GaAs/AlGaAs quantum well using optical transient grating spectroscopy [PDF]
We use phase-resolved transient grating spectroscopy to measure the drift and diffusion of electron-hole density waves in a semiconductor quantum well.
D. R. Tibbetts +9 more
core +1 more source
OPTICAL PROPERTIES OF CdS QUANTUM DOTS SYNTHESIZED AT DIFFERENT CONCENTRATIONS OF REAGENTS
. The paper presents the results of the investigation of quantum dots of cadmium sulfi de synthesized by sol-gel technology in a gelatin matrix. Samples were obtained with different contents of the initial reagents. The concentrations were varied from 2·
Victor G. Klyuev +2 more
doaj +1 more source
West Nile Virus Capsid Protein Interacts With Biologically Relevant Host Lipid Systems
West Nile and dengue viruses are closely related flaviviruses, originating mosquito-borne viral infections for which there are no effective and specific treatments.
Ana S. Martins +4 more
doaj +1 more source
Spectroscopy of quadrupole and octupole states in rare-earth nuclei from a Gogny force [PDF]
Collective quadrupole and octupole states are described in a series of Sm and Gd isotopes within the framework of the interacting boson model (IBM), whose Hamiltonian parameters are deduced from mean field calculations with the Gogny energy density ...
Nomura, K. +2 more
core +4 more sources
High‐speed atomic force microscopy: Imaging and force spectroscopy
Atomic force microscopy (AFM) is the type of scanning probe microscopy that is probably best adapted for imaging biological samples in physiological conditions with submolecular lateral and vertical resolution. In addition, AFM is a method of choice to study the mechanical unfolding of proteins or for cellular force spectroscopy.
Eghiaian, Frédéric +4 more
openaire +3 more sources
A guide to magnetic tweezers and their applications
Magnetic force spectroscopy is a rapidly developing single molecule technique that found numerous applications at the interface of physics and biology. Since the invention of the first magnetic tweezers, a number of modifications were incorporated into ...
Rupa Sarkar, Valentin V Rybenkov
doaj +1 more source
Probing Ligand-Receptor Interaction in Living Cells Using Force Measurements With Optical Tweezers
This work probes the binding kinetics of COOH-terminus of Clostridium perfringens enterotoxin (c-CPE) and claudin expressing MCF-7 cells using force spectroscopy with optical tweezers.
Carolin Riesenberg +10 more
doaj +1 more source

