Results 61 to 70 of about 529,798 (193)

Probing protein-protein interactions by dynamic force correlated spectroscopy (FCS)

open access: yes, 2005
We develop a formalism for single molecule dynamic force spectroscopy to map the energy landscape of protein-protein complex ($P_1$$P_2$). The joint distribution $P(\tau_1,\tau_2)$ of unbinding lifetimes $\tau_1$ and $\tau_2$ measurable in a compression ...
A. Ashkin   +4 more
core   +1 more source

Statistics of reversible bond dynamics observed in force-clamp spectroscopy

open access: yes, 2010
We present a detailed analysis of two-state trajectories obtained from force-clamp spectroscopy (FCS) of reversibly bonded systems. FCS offers the unique possibility to vary the equilibrium constant in two-state kinetics, for instance the unfolding and ...
Andreas Janshoff   +5 more
core   +1 more source

Force Measurement Enabling Precise Analysis by Dynamic Force Spectroscopy [PDF]

open access: yesInternational Journal of Molecular Sciences, 2011
Dynamic force spectroscopy (DFS) makes it possible to investigate specific interactions between two molecules such as ligand-receptor pairs at the single-molecule level. In the DFS method based on the Bell-Evans model, the unbinding force applied to a molecular bond is increased at a constant rate, and the force required to rupture the molecular bond ...
Taninaka, Atsushi   +3 more
openaire   +2 more sources

Simulation-based inference of single-molecule force spectroscopy

open access: yesMachine Learning: Science and Technology, 2023
Single-molecule force spectroscopy (smFS) is a powerful approach to studying molecular self-organization. However, the coupling of the molecule with the ever-present experimental device introduces artifacts, that complicate the interpretation of these ...
Lars Dingeldein   +2 more
doaj   +1 more source

Structure and spectroscopy of surface defects from scanning force spectroscopy: theoetical predictions [PDF]

open access: yes, 2000
A possibility to study surface defects by combining noncontact scanning force microscopy (SFM) imaging with atomically resolved optical spectroscopy is demonstrated by modeling an impurity Cr3+ ion at the MgO(001) surface with a SFM tip.
Kantorovich, LN   +2 more
core  

Graphene on Rh(111): STM and AFM studies

open access: yes, 2012
The electronic and crystallographic structure of the graphene/Rh(111) moir\'e lattice is studied via combination of density-functional theory calculations and scanning tunneling and atomic force microscopy (STM and AFM).
A. Thissen   +5 more
core   +1 more source

Polynomial force approximations and multifrequency atomic force microscopy

open access: yesBeilstein Journal of Nanotechnology, 2013
We present polynomial force reconstruction from experimental intermodulation atomic force microscopy (ImAFM) data. We study the tip–surface force during a slow surface approach and compare the results with amplitude-dependence force spectroscopy (ADFS ...
Daniel Platz   +3 more
doaj   +1 more source

Atomic Force Spectroscopy on Ionic Liquids

open access: yesApplied Sciences, 2019
Ionic liquids have become of significant relevance in chemistry, as they can serve as environmentally-friendly solvents, electrolytes, and lubricants with bespoke properties.
Christian Rodenbücher   +2 more
doaj   +1 more source

Single-molecule force spectroscopy of protein-membrane interactions

open access: yeseLife, 2017
Many biological processes rely on protein–membrane interactions in the presence of mechanical forces, yet high resolution methods to quantify such interactions are lacking.
Lu Ma   +8 more
doaj   +1 more source

Single-Molecule Mechanics in Ligand Concentration Gradient

open access: yesMicromachines, 2020
Single-molecule experiments provide unique insights into the mechanisms of biomolecular phenomena. However, because varying the concentration of a solute usually requires the exchange of the entire solution around the molecule, ligand-concentration ...
Balázs Kretzer   +5 more
doaj   +1 more source

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