Results 231 to 240 of about 176,515 (293)

CRISPR/Cas9‐Based Vanadium MXene‐Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal‐Induced Multi‐Effect Synergistic Antitumor Therapy

open access: yesAdvanced Science, EarlyView.
In this study, a MXene‐based V4C3 nanoplatform, VARH, was constructed, which achieved a photothermal conversion efficiency of 44.21% in the NIR‐II window. This platform integrated photothermal therapy, chemodynamic therapy, and thermodynamic therapy with CRISPR/Cas9‐mediated heat shock protein 90 knock‐out technology.
Zi‐Jian Huang   +8 more
wiley   +1 more source

Nucleation Kinetics Reveals a Distinct Biological Function Space of Biomolecular Condensates

open access: yesAdvanced Science, EarlyView.
This study utilizes microfluidics to quantify the nucleation rates of dense liquid phases within dilute solutions and of the reverse process, in which dilute voids nucleate inside condensates. The interfacial tension is identified as the key determinant of both processes.
Leif‐Thore Deck   +5 more
wiley   +1 more source

Self‐Assisted Charge Storage‐Release Mechanism Enabling Flexible Design of Biomimetic Triboelectric Nanogenerators

open access: yesAdvanced Science, EarlyView.
Inspired by the mimosa, this study develops a flexible triboelectric nanogenerator with a novel microneedle array and battery‐mimetic architecture. The device introduces a spontaneous charge self‐regulation mechanism that confines the electric field below the air breakdown threshold, and achieves an outstanding charge density of 396.50 µC m−2 ...
Hanpeng Gao   +7 more
wiley   +1 more source

Armed conflict exposure types are not equally associated with access to psychosocial support: A study of over 8 million victims of the Colombian armed conflict. [PDF]

open access: yesInt J Soc Psychiatry
Constable Fernandez C   +7 more
europepmc   +1 more source

Highly Aligned Bacteria Cellulose Yarn Aggregation for Energy Generation and Strain Sensing

open access: yesAdvanced Science, EarlyView.
Although high‐performance bacterial cellulose fibers have attracted significant interest for wearable electronics, a self‐powered and high‐mechanosensitive design is still scarce for achieving an intelligent integrated system. Here, we demonstrate an innovative bio‐fabrication strategy to develop a core‐sheath yarn that features the ordered network and
Chong Gao   +9 more
wiley   +1 more source

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

open access: yesAdvanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang   +23 more
wiley   +1 more source

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