Results 161 to 170 of about 6,493,577 (290)

Impulse Oscillometry Detected Physiological Abnormalities More Frequently Than Spirometry in Children With Largely Preserved Lung Function

Acta Paediatrica, EarlyView.
ABSTRACT Aim We compared how well impulse oscillometry (IOS) and spirometry detected small airway dysfunction (SAD) in children with asthma and evaluated associations between IOS abnormalities, asthma control, and asthma severity. Methods This observational study comprised 106 children aged 6–18 years with asthma who underwent IOS and spirometry before
Paola Di Filippo, Annamaria Porreca, Duilio Petrongari, Massimiliano Raso, Benedetta Ciccone, Sabrina Di Pillo, Francesco Chiarelli, Marina Attanasi   +7 more
wiley   +1 more source

Expiratory time constant patterns reveal obstructive lung mechanics in non-obstructive spirometry. [PDF]

PLOS Digit Health
Depta F, Bhatt SP, Heinz M, Černý R, Koblížek V, Pobeha P.   +5 more
europepmc   +1 more source

The discovery and development of ensifentrine: A novel inhaled dual PDE3/4 inhibitor having ‘bifunctional’ bronchodilator and anti‐inflammatory activity

British Journal of Pharmacology, EarlyView.
Abstract Ensifentrine (formerly called RPL 554) is a novel, first in class, inhaled bifunctional dual PDE3/4 inhibitor for the treatment of chronic respiratory diseases. Ensifentrine exhibits both bronchodilation via PDE3 inhibition and anti‐inflammatory activity via PDE4 inhibition.
Clive Page
wiley   +1 more source

Lung Function-Based Assessment of Small Airway Dysfunction in Chronic Respiratory Diseases. [PDF]

Biology (Basel)
Liwsrisakun C, Deesomchok A, Pothirat C, Chaiwong W.   +3 more
europepmc   +1 more source

Correlation of BMI With Dynamic Pulmonary Function Indices in Nonobese Young Adults: A Cross-Sectional Study. [PDF]

Cureus
Kumari A, Bara MP, Sinha MBK, Sinha RK.
europepmc   +1 more source

Inflammatory Mediators Associated With Corticosteroid Responsiveness During Asthma Attacks

Clinical &Experimental Allergy, EarlyView.
ABSTRACT Higher baseline sputum/serum eotaxin‐3 and serum IL‐5 levels were associated with greater FEV1 improvement following OCS during asthma attacks. Corticosteroid‐induced inflammatory modulation differed across T2 phenotypes during asthma attacks.
Carlos Celis‐Preciado, Elsa Ben Hamou Kuijpers, Mohamed‐Ilias Kourid, Simon Leclerc, Martine Duval, Dominic O. Cliche, Félix‐Antoine Vézina, Pierre Larivée, Samuel Lemaire‐Paquette, Philippe Lachapelle, Martin Klein, Simon Couillard   +11 more
wiley   +1 more source

Navigating the small airways with tezepelumab. [PDF]

ERJ Open Res
Lim JV, Kuo CR, Chan R.
europepmc   +1 more source

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

Clinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole, Ingrid Laing, Ryan Mead‐Hunter, Peter Le Souef, Guicheng Zhang   +4 more
wiley   +1 more source

Effects of Noninvasive Cervical Vagal Nerve Stimulation on Cognitive Performance But Not Brain Activation in Healthy Adults

Neuromodulation: Technology at the Neural Interface, EarlyView., 2020
Abstract Objectives While preliminary evidence suggests that noninvasive vagal nerve stimulation (nVNS) may enhance cognition, to our knowledge, no study has directly assessed the effects of nVNS on brain function and cognitive performance in healthy individuals.
Ruth Klaming, Alan N. Simmons, Andrea D. Spadoni, Imanuel Lerman   +3 more
wiley   +1 more source

Chinese Expert Consensus on the Testing Process, Quality Control and Clinical Application of Fractional Exhaled Nitric Oxide (2025). [PDF]

Clin Respir J
Qu Y, Li L, Guo J, Zhou Y, Gong Y, Chen Z, Song Y, Task Force for Pulmonary Function of Chinese Thoracic Society.   +7 more
europepmc   +1 more source