Results 191 to 200 of about 8,512,443 (291)

Prognostic marker for severe acute exacerbation of chronic obstructive pulmonary disease: analysis of diffusing capacity of the lung for carbon monoxide (D_LCO) and forced expiratory volume in one second (FEV₁). [PDF]

BMC Pulm Med, 2021
Choi J, Sim JK, Oh JY, Lee YS, Hur GY, Lee SY, Shim JJ, Rhee CK, Min KH.   +8 more
europepmc   +1 more source

Natural History of Alternaria Sensitisation and Association With Asthma and Rhinitis From Childhood to Adulthood

Allergy, EarlyView.
We aimed to characterise Alternaria sensitisation trajectories from childhood to adulthood; we compared SPT, whole‐extract sIgE and rAlt a 1, and assessed their longitudinal association with asthma and rhinitis in the Isle of Wight birth cohort. Alternaria sensitisation in the Isle of Wight Birth Cohort emerges mainly in late adolescence and, when ...
Mohammad Leily, Hongmei Zhang, Graham Roberts, Pandurangan Vijayanand, Magnus Borres, Eva Södergren, Ramesh J. Kurukulaaratchy, S. Hasan Arshad   +7 more
wiley   +1 more source

Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling of Dupilumab on Pre-Bronchodilator Forced Expiratory Volume in 1 Second (FEV₁) in Uncontrolled Moderate-To-Severe Asthma. [PDF]

CPT Pharmacometrics Syst Pharmacol
Zhang L, Davis JD, Kanamaluru V, Xu C.
europepmc   +1 more source

Efficacy and Safety of Dupilumab in Chinese Adult Patients With Chronic Rhinosinusitis With Nasal Polyps: A Randomized, Placebo‐Controlled, Phase III Trial

Allergy, EarlyView.
Dupilumab significantly improved nasal polyp score, nasal congestion, olfaction, total symptom score, and disease‐specific quality of life in Chinese patients with uncontrolled CRSwNP. Incidence of treatment‐emergent adverse events was similar between dupilumab and placebo.
Mu Xian, Menglin Wang, Changqing Zhao, Lijia Wan, Yu Xu, Juan Meng, Rui Xu, Xicheng Song, Li Shi, Yucheng Yang, Yan Jiang, Yanzhen Wu, Bethany Ling, Vivian Li, Andrew P. Fontenot, Lacey R. Robinson, Neelam A. Phadke, Chengshuo Wang, Luo Zhang   +18 more
wiley   +1 more source

Preoperative forced expiratory volume in one second and postoperative respiratory outcomes in nonpulmonary and noncardiac surgery: a retrospective cohort study. [PDF]

JA Clin Rep
Mizota T, Hamada M, Hirotsu A, Dong L, Matsukawa S, Takeda C, Egi M.   +6 more
europepmc   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Increased risk of respiratory events during endobronchial ultrasound examination in patients with reduced forced expiratory volume: a prospective observational study. [PDF]

Front Med (Lausanne)
Grünewaldt A, Rohde G.
europepmc   +1 more source

Comparison of predicted postoperative forced expiratory volume in the first second (FEV1) using lung perfusion scintigraphy with observed forced expiratory volume in the first second (FEV1) post lung resection. [PDF]

World J Nucl Med, 2020
Mathew B, Nag S, Agrawal A, Ranganathan P, Purandare NC, Shah S, Puranik A, Rangarajan V.   +7 more
europepmc   +1 more source

Efficacy and Safety of Intralymphatic Immunotherapy With Grass Allergoid and Microcrystalline Tyrosine: A Double‐Blind Randomised Placebo‐Controlled Trial

Allergy, EarlyView.
This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of
Lara Šošić, Stephan C. Flory, Claudia C. V. Lang, Emma C. Widmer, Alexandra Chabot, Johannes M. Schmid, Tobias Andermatt, David Melillo, Bjarke Hviid‐Vyff, Maibritt Mardahl, Peter Schmid‐Grendelmeier, Thomas M. Kündig, Hans Jürgen Hoffmann, Pål Johansen   +13 more
wiley   +1 more source

Vog: Using Volcanic Eruptions to Estimate the Health Costs of Particulates

The Economic Journal, EarlyView., 2018
The negative consequences of long‐term exposure to particulate pollution are well established but a number of studies find no effect of short‐term exposure on health outcomes. The high correlation of industrial pollutants complicates the estimation of the impact of individual pollutants on health.
Timothy J. Halliday, John Lynham, Áureo de Paula   +2 more
wiley   +1 more source