Results 51 to 60 of about 79,262 (293)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

25 years of forced migration [PDF]

, 2012
During the past 25 years, Forced Migration Review (FMR) has played a vital role in enabling researchers, practitioners and policymakers to exchange information and ideas on refugee-related issues.
Crisp, Jeff
core   +1 more source

Cohort profile: Resettlement in Uprooted Groups Explored (REFUGE)—a longitudinal study of mental health and integration in adult refugees from Syria resettled in Norway between 2015 and 2017

BMJ Open, 2020
Purpose In the field of forced migration and mental health research, longitudinal studies with large sample sizes and rigorous methodology are lacking.
Fredrik Saboonchi, Alexander Nissen, Prue Cauley, Arnfinn Andersen, Øivind Solberg   +4 more
doaj   +1 more source

Priorities for addressing substance use disorder in humanitarian settings

Conflict and Health, 2021
Background Populations affected by humanitarian emergencies are vulnerable to substance (alcohol and other drug) use disorders, yet treatment and prevention services are scarce.
M. Claire Greene, Stephanie Haddad, Anja Busse, Nadine Ezard, Peter Ventevogel, Lina Demis, Sachi Inoue, Jan-Christopher Gumm, Giovanna Campello, Wietse A. Tol, Jeremy C. Kane   +10 more
doaj   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

Advanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

g7+ [PDF]

, 2013
Eighteen countries recognised as fragile states and clustering around the high end of the Failed States Index convene under the name 'g7plus', with the motto 'Goodbye conflict, welcome development'

core   +1 more source

Health information management in the context of forced migration in Europe [PDF]

, 2020
Zenner D, Kolitha W, Bozorgmehr K, et al. Health information management in the context of forced migration in Europe. In: Fargues P, Rango M, Borgnäs E, Schöfberger I, International Organization for Migration - Global Migration Data Analysis Centre, eds.
Borgnäs, Emma, Kolitha, Wickramage, Abdelkarim-Spiekerma, Mariam, Schöfberger, Irene, Maateli, Alberto, Campos-Matos, Ines, Zenner, Dominik, Rango, Marzia, International Organization for Migration - Global Migration Data Analysis Centre, Marchese, Valentina, Bozorgmehr, Kayvan ; https://orcid.org/, Fargues, Philippe   +11 more
core  

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source