Results 81 to 90 of about 1,911,339 (388)

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

Introducing Forced Migration

open access: yes, 2021
At a time when global debates about the movement of people have never been more heated, this book provides readers with an accessible, student-friendly guide to the subject of forced migration. Readers of this book will learn who forced migrants are, where they are and why international protection is critical in a world of increasingly restrictive ...
openaire   +2 more sources

Local Governance Quality and the Environmental Cost of Forced Migration

open access: yesJournal of Development Economics, 2020
Can high-quality local governance alleviate the environmental impact of large-scale refugee migration? The recent surge in refugee flows has brought additional challenges to local governments in Europe, the Middle East, and certain regions of Africa and ...
C. Aksoy, Semih Tumen
semanticscholar   +1 more source

Glycodelin suppresses endometrial cell migration and invasion but stimulates spheroid attachment [PDF]

open access: yes, 2012
Glycodelin contains four isoforms with diverse biological functions. Glycodelin-A is potentially a diagnostic marker for cancer patients and receptivity marker of the secretory endometrium.
Lee, CL, Lee, KF, So, KH, Yeung, WSB
core   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Forced Migration in Sub-Saharan Africa

open access: yesVestnik RUDN. International Relations, 2019
Migration is an important issue in modern international relations. This article discusses the characteristics of forced migration in Sub-Saharan Africa (SSA).
Joaddan Prisca Kommegni Fongang
doaj   +1 more source

Climate Change and Forced Migration

open access: yesMigraciones Internacionales, 2020
The population of environmentally displaced people has increased recently, thus this article aims to address the challenges climate change may impose on Nation-States concerning human rights in relation to forced migration.
Shirley Llain Arenilla   +1 more
semanticscholar   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

A Double-Edged Sword? The Role of Digital Technologies in Marriage and Divorce Among Syrian Refugees in Northern Jordan

open access: yesRefuge
This paper explores how young Syrian refugees in Jordan who have grown up using information and new communication technologies are using the internet as a private space where emotions and practices regarding intimate and marital life are expressed.
Ruba Al Akash   +2 more
doaj   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

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