Results 31 to 40 of about 166,660,675 (310)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

FORCES THAT ENHANCE OR REDUCE EMPLOYEE RESISTANCE TO CHANGE [PDF]

Annals of the University of Oradea: Economic Science, 2013
This paper is part of change management. The extent to which managers succeed to reduce the resistance to change from the part of the affected employees contributes greatly to the achievement of the targeted objectives that follow a change process.
Prediscan Mariana, Bradutanu Daniela, Roiban Roxana Nadina,   +3 more
doaj  

Numerical Investigation of Impinging Planar Shock Wave Interaction with Axisymmetric Slender Body [PDF]

Journal of Applied Fluid Mechanics
Shock Wave Boundary Layer Interactions represent a complex flow feature combining high-speed inertial force - dominated flows with low-speed viscous force dominated regions.
M. A. Ali, P. Mondal
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Driving forces of main landscape change processes from past 200 years in Central Europe - differences between old democratic and post-socialist countries

Ekológia (Bratislava), 2016
The article compares and points out differences in driving forces of four main landscape change processes that shaped post-socialist countries and old democratic countries of Central Europe during the last two centuries.
Skokanová Hana, Falťan Vladimír, Havlíček Marek   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Potential effects of climate change .... Spanish

, 2023
Title from PDF caption (viewed on February 9, 2023).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Artificial intelligence as a factor of change in the use of military forces [PDF]

Međunarodna politika
The relationship between science, technology, war, and military forces that manifests in multidimensional space represents a non-linear system. The tendency to create an orderly system from the non-linear is natural.
Aleksandar Pavić, Hatidža Beriša, Katarina Jonev Ćiraković   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source