Results 51 to 60 of about 251,793 (312)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

On growth and force: mechanical forces in development [PDF]

open access: yesDevelopment, 2020
ABSTRACTThe EMBO/EMBL Symposium ‘Mechanical Forces in Development’ was held in Heidelberg, Germany, on 3-6 July 2019. This interdisciplinary symposium brought together an impressive and diverse line-up of speakers seeking to address the origin and role of mechanical forces in development.
Hallou, A, Brunet, T
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Observational estimates of radiative forcing due to land use change in southwest Australia

open access: yes, 2007
Radiative forcing associated with land use change is largely derived from global circulation models (GCM), and the accuracy of these estimates depends on the robustness of the vegetation characterization used in the GCMs.
Christopher, S.A.   +13 more
core   +1 more source

Effect of planting time and supplemental irradiation on growth and flowering of Lachenalia 'Romaud'

open access: yesHorticultural Science, 2019
Growth and flowering of lachenalia 'Romaud' was studied with reference to its commercial potential as pot plant and the need to obtain flowering plants at a specific time. The experiment was carried out in a heated glasshouse.
Anna Kapczyńska
doaj   +1 more source

“60 Years on”—Effects of Climatic Change on Tree Phenology—A Case Study Using Pome Fruit

open access: yesHorticulturae, 2022
Phenological records of apple and pear trees, including flowering, harvest and leaf drop, and concomitant weather records at Klein-Altendorf (50° N) near Bonn, Germany were correlated using two approaches: (a) linear curve fitting and (b) comparison of ...
Achim Kunz, Michael Blanke
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Climate forcing and desert malaria: the effect of irrigation. [PDF]

open access: yes, 2011
BACKGROUND: Rainfall variability and associated remote sensing indices for vegetation are central to the development of early warning systems for epidemic malaria in arid regions.
Srivastava Harish C   +17 more
core   +1 more source

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