Results 101 to 110 of about 127,126 (260)

Arthrogryposis Multiplex Congenita in Pediatric Age: Correlation Between MUScular MRI and Functional Evaluation (AMUSE), Toward a Biomechanical Model

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) is a group of diseases with joint limitations at two or more distinct joint levels at birth. Joint limitations are not progressive, but the functional consequences have a lifelong impact on patients. The management of these conditions is therefore demanding, necessarily multidisciplinary, and is a long ...
Alicia‐Marine Milot, Mariya Raykova, Claire Huzar, Véronique Thellier, Nicolas Hergibo, Marjolaine Gauthier, Gipsy Billy‐Lopez, Chantal Durand, Frédérique Nugues, Véronique Bourg, Klaus Dieterich   +10 more
wiley   +1 more source

Postcranial anatomy and osteohistology of an early prozostrodont cynodont from the Upper Triassic of Brazil

The Anatomical Record, EarlyView.
Abstract Prozostrodon brasiliensis, a probainognathian cynodont of the clade Prozostrodontia, is recognized as a key taxon for understanding the origin of Mammaliaformes and mammals. Despite detailed investigations of its cranial anatomy, the postcranial skeleton has received comparatively less attention.
Iasmim M. Michelotti, Lívia Roese‐Miron, Brodsky Dantas Macedo Farias, Marina Bento Soares, Leonardo Kerber   +4 more
wiley   +1 more source

Evolutionary morphology of the haplorhine hamate

The Anatomical Record, EarlyView.
Abstract Primates adopt a variety of hand postures during an impressive diversity of locomotor and manipulative behaviors. Morphological research has found that elements of the hand skeleton, such as the hamate, hold key information for inferring hand use and locomotor kinematics in extinct species.
Laura E. Hunter, Matthew W. Tocheri, Caley M. Orr, Biren A. Patel, Zeresenay Alemseged   +4 more
wiley   +1 more source

Scaling and ecomorphology of lagomorph body shape and appendicular skeleton

The Anatomical Record, EarlyView.
Abstract Body shape is one of the most prominent features of phenotypic variation. Yet, mammalian body shapes are poorly quantified and the underlying components contributing to its diversity and its relationship to other skeletal components are rarely tested.
Nia Brice, Coby Huizenga, Chris J. Law
wiley   +1 more source

Variable grouping patterns in primates: A test of the better competitor hypothesis in male Verreaux's sifaka (Propithecus verreauxi)

The Anatomical Record, EarlyView.
Abstract Intraspecific variation in social organization (IVSO) within primate populations can arise due to male mating competition. Verreaux's sifaka (Propithecus verreauxi) populations exhibit both single‐male and multi‐male groups, providing an opportunity to examine the relationship between male competitive ability and social organization.
Lemeng Li, Stacey R. Tecot, Rebecca J. Lewis   +2 more
wiley   +1 more source

Local variation in age‐related cortical expansion within and between cross‐sections of distal human long bones

The Anatomical Record, EarlyView.
Abstract Cortical bone expansion is an age‐related process where, through endosteal resorption and periosteal apposition, cross‐sectional diameter increases while cortical thickness decreases in long bone diaphyses. Local variation has been observed in this process between cross‐sectional locations, but few studies have examined directional variation ...
Gregory J. Wehrman, Alice F. Gooding, Adam D. Sylvester, Dawnie W. Steadman, Benjamin M. Auerbach   +4 more
wiley   +1 more source

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

The synergistic impact of granulocytic myeloid‐derived suppressor cells and innate lymphoid cells in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Systemic sclerosis (SSc) is a chronic autoimmune disorder characterized by immune dysregulation and fibrosis, with myeloid‐derived suppressor cells (MDSCs) emerging as important regulators of immune responses. However, the role of MDSCs in SSc‐associated fibrosis and their interactions with other immune cell populations remain poorly ...
Stefanie Weber, Mario R. Angeli, Hashem Mohammadian, Hannah Labinsky, Maria Gabriella Raimondo, Richard Demmler, Yuko Ariza, Thomas Wohlfahrt, Markus Luber, Yi‐Nan Li, Jörg H.W. Distler, Tobias Bäuerle, Georg Schett, Simon Rauber, Andreas Ramming, Alina M. Ramming   +15 more
wiley   +1 more source

Dissection versus prosection by anatomical region: Evaluating a regional group dissection curriculum in medical education

Anatomical Sciences Education, EarlyView.
Abstract Gross anatomy education has undergone significant changes due to evolving curricular demands, leading to reduced hands‐on dissection opportunities in many medical schools. The purpose of this study was to compare the academic performance of medical student dissectors and those assigned to prosection‐based learning across anatomical regions ...
Andrew J. Gaetano, Jason Howard, Luke Ritter, Maha Khan, Nicolas Jozefowski, Eva L. Murdoch   +5 more
wiley   +1 more source