Results 291 to 300 of about 1,369,551 (340)

Deterministic nowcasting of geostationary satellite infrared brightness temperature using 3D U-Net diffusion model. [PDF]

Sci Rep
Afzali Gorooh V, Delle Monache L, Axisa D, Sengupta A, Zhang Z, Ralph FM.   +5 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Adaptive demand forecasting framework with weighted ensemble of regression and machine learning models along life cycle variability. [PDF]

Sci Rep
Hammam IM, El-Kharbotly AK, Sadek YM.
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Explainable dual LSTM-autoencoders with exogenous features for anomaly detection and supply chain forecasting. [PDF]

Sci Rep
Xiaoyang C.
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Spatio-temporal trends, distribution and prediction of tuberculosis incidence in Uganda (2020-2025). [PDF]

BMC Infect Dis
Aturinde A, Amanya G, Ikwangu R.
europepmc   +1 more source

Assimilation of high-resolution Ocean Color Monitor (OCM) aerosol optical depth in WRF-Chem improves PM₂.₅ forecasts over the Indian region. [PDF]

Sci Rep
Yadav PP, Ghude SD, Kumar R, Govardhan G, Jat R, Shah S, Shukla BP, Mishra MK, Putrevu D, Thapliyal PK, Sharma R.   +10 more
europepmc   +1 more source

Forecasting cashew production in India using a hybrid machine learning framework with STL decomposition, ensemble methods, and global trade network analysis. [PDF]

Sci Rep
C S, A P.
europepmc   +1 more source