Results 171 to 180 of about 524,481 (298)

Digital Prescription-Based Influenza Activity Forecasting in Jiangxi Province, China: Comparative Modeling Analysis Using Multisource Data. [PDF]

J Med Internet Res
Yang R, Xu Z, Zhang C, Qiu L, Qian J, Liu J, Dong Y, Zeng Z, Shen R, Feng L.   +9 more
europepmc   +1 more source

Forecasting with DSGE models [PDF]

In this paper we review the methodology of forecasting with log-linearised DSGE models using Bayesian methods. We focus on the estimation of their predictive distributions, with special attention being paid to the mean and the covariance matrix of h-step
Warne, Anders, Coenen, Günter, Christoffel, Kai   +2 more
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Entropy-Driven Volatility Prediction for ETF Quantitative Investment in the Chinese Stock Market: A Machine Learning Framework for Barbell Strategy Optimization. [PDF]

Entropy (Basel)
Yan K, Yue Z, He Q, Li Y.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Deep learning techniques for extreme rainfall prediction: a review of state-of-the-art. [PDF]

Front Artif Intell
Mukhalela BU, Viriri S, Ndzi D, Gebreslasie M, Zeeshan Shakir M, Ramzan N, Ayaz F, Lynch M, Spencer LH, Naidoo S, Nadesan-Reddy N, Mahomed O, Dickinson N, Henriquez F.   +13 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Deep forecasting architectures mirror ecological time scales in water quality prediction. [PDF]

Environ Sci Ecotechnol
Yu Y, Zhang M, Liang Z, Qu F, Wang Y, Kong X, Rinke K, Chen N.   +7 more
europepmc   +1 more source

Weather/forecasting: a fishers’ forecaster

, 2018
Action research by the University of Sussex is bringing fishermen and scientists together to track wind, and waves and save lives. Seen from the air, Thiruvananthapuram, the capital city of Kerala state in south India, looks like a magic carpet – a long strip of golden sand separating a vast green canopy of coconut palms and the turquoise shimmer of ...
openaire   +2 more sources

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source