Results 71 to 80 of about 359,388 (302)

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Spontaneous migration of periocular glass foreign body: An interesting case

Kerala Journal of Ophthalmology, 2017
The occurrence of soft-tissue foreign bodies (FBs) in and around the orbit is often seen after trauma. Wound exploration and removal of the embedded materials is the standard of care. Relevant investigations help to detect retained FBs in suspected cases.
Padma B Prabhu, Deepak Vellarikkal, Babitha Valiayaveettil   +2 more
doaj   +1 more source

"The Prospects for Policy-Change in EU Asylum Policy: Venue and Image at the European Level" [PDF]

, 2007
The upgrading of the European Commission and the European Parliament’s role in the EU policy-process from 1999 might have been expected to herald a shift away from the previous security- and control-orientation of asylum policy.
Maurer, Andreas,, Parkes, Roderick.
core   +1 more source

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Hepatic Abscess Secondary to Stomach Perforation by a Fish Bone: a Rare Cause of Hepatic Abscess

Annals of Hepatology, 2018
Gastrointestinal foreign bodies are commonly encountered in clinical practice. However, although perforation of the gastrointestinal tract by a foreign body is not unusual, the formation of a hepatic abscess as a result of the migration of a foreign body
Wenxiu Yu, Hailin Yu, Jun Ling, Jiang Du, Zhijing Yin, Chengen Li, Min Zhou   +6 more
doaj   +1 more source

Migration-selection balance at multiple loci and selection on dominance and recombination [PDF]

, 2013
A steady influx of a single deleterious multilocus genotype will impose genetic load on the resident population and leave multiple descendants carrying various numbers of the foreign alleles.
Proulx, Stephen R., Yanchukov, Alexey
core   +4 more sources

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

Advanced Science, EarlyView.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou, Qingyuan Wu, Yang Wu, Runzhe Huang, Wei Li, Hanjie Niu, Hongtao Sun, Huiyu Liu   +7 more
wiley   +1 more source

Migrating Foreign Body Bronchus: An Unusual Case of Foreign Body Aspiration

Case Reports in Clinical Medicine, 2014
Foreign bodies [FB] in the bronchus are important causes of morbidity and mortality in paediatric age group and pose diagnostic and therapeutic challenges. Inert and smooth foreign bodies are prone for migration from one side to other due to minimal inflammatory process and easy mobility.
Ram Badan Singh, Ajay Narayan Gangopadhyay, Dinesh Kumar Gupta, Vaibhav Pandey   +3 more
openaire   +2 more sources