T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Pirfenidone inhibits fibrosis in foreign body reaction after glaucoma drainage device implantation
Drug Design, Development and Therapy, 2016 Kyoung In Jung, Chan Kee ParkDepartment of Ophthalmology and Visual Science, Seoul St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South KoreaBackground: The aim of this study was to investigate the antiscarring ...
Jung KI, Park CK
doaj
Surgical Management of Penile Lesions Secondary to Foreign Body Reaction: A Case Report and Systematic Review [PDF]
, 2017 Pedro Leonardo Sanches Faveret +1 more
openalex +1 more source
Citation: 'foreign body reaction' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13932 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire +1 more source
Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency
Advanced Science, EarlyView.Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu +23 more
wiley +1 more source
Novel Vascular‐Adaptive Liquid Metal Microspheres Enable Visualized Arterial Embolization Therapy
Advanced Science, EarlyView.We present drug‐loaded liquid metal microspheres (X‐MEN) as a novel agent for image‐guided arterial embolization. With inherent radiopacity and superior deformability, X‐MEN enables real‐time monitoring and conforms tightly to irregular vessels. This approach ensures precise, long‐lasting embolization without recanalization, addressing critical ...
Chenyu Shen +14 more
wiley +1 more source
Dexamethasone Reduces the Foreign Body Reaction to Intraneural Electrode Implants in the Peripheral Nerve of the Rat [PDF]
, 2018 Natàlia de la Oliva +2 more
openalex +1 more source
Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects
Advanced Science, EarlyView.Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang +9 more
wiley +1 more source
Histological Analysis of Early Osteolysis in Total Ankle Arthroplasty
Foot & Ankle Orthopaedics, 2017 Category: Ankle Arthritis Introduction/Purpose: The purpose of this study was to perform a histological comparative analysis of tibiotalar joint samples taken from areas of osteolysis adjacent to total ankle arthroplasties vs control synovial specimens ...
Oliver Schipper MD, Steven Haddad MD
doaj +1 more source
Epidermal inclusion cyst with foreign-body giant-cell reaction treated with surgical excision and rotational flap closure: A case report [PDF]
, 2018 Nathaniel LP Preston +2 more
openalex +1 more source