Results 181 to 190 of about 1,476,984 (298)

Closing the Loop: High‐Precision 3D Photofabrication in Living Tissues

open access: yesAdvanced Science, EarlyView.
Writing 3D microstructures inside living tissue demands more than laser access; It demands information. Hierarchical sensing captures thermal and mechanical states across pulse‐train, voxel, and structure timescales, feeding a controller that steers the laser in real time.
Amirbahador Zeynali   +2 more
wiley   +1 more source

Architected Load Paths Enable Stiffening and Motion Programming in Soft Pneumatic Actuators

open access: yesAdvanced Science, EarlyView.
A single MARS template introduces an architected reinforcement strategy for programmable soft pneumatic actuators through internal structural organization and selective beam removal. This monolithic architecture enables deformation reconfiguration from continuous bending to joint‐like articulation and torsional motion, allowing one compliant platform ...
Jie Wang   +6 more
wiley   +1 more source

Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation

open access: yesAdvanced Science, EarlyView.
Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu   +10 more
wiley   +1 more source

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

open access: yesAdvanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

open access: yesAdvanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu   +10 more
wiley   +1 more source

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

open access: yesAdvanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang   +9 more
wiley   +1 more source

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